ArticleSafety and health at work2025
Job Loss and Early-onset Dementia Risk in Middle-aged Adults: A Longitudinal Study.
Article in Safety and health at work, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Employment Experiences of People Living with Young-Onset Dementia: Perspectives from Workers, Care Partners, and Employment Specialists in Taiwan.Journal of occupational rehabilitation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Early-onset dementia poses a significant public health challenge, particularly due to its profound impact on working-age individuals (under 65 years). This study investigated the association between job loss and early-onset dementia in middle-aged adults in Republic of Korea. Methods: Using National Health Insurance Service data in the Republic of Korea, we analyzed participants aged 45-54 years who were employed by private companies and who underwent health checkups between 2009 and 2010. Early job loss was defined as involuntary unemployment within two years of the 2011 index date. The primary outcome was incident dementia, identified using both International Classification of Diseases-10 (ICD-10) codes and antidementia medication use. Adjusted hazard ratios (HRs) were calculated using Cox proportional hazards models. Subgroup analyses were conducted by age, household income, residential region, company size, and industrial sector. Results: Among 1,130,665 participants (mean age 49.2 ± 2.82 years, follow-up of 14.02 years), early-onset dementia occurred in 3,748 individuals. Of these, 580 cases were from the job loss group ( Conclusion: Job loss was significantly associated with an increased risk of early-onset dementia, particularly among males, after adjusting for multiple demographic, socioeconomic, and health-related covariates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.