Evidence map›Paper›PMID 41477006›Full record

ArticleFrontiers in cellular and infection microbiology2025

Clinical, genomic, and functional characterization of vancomycin-resistant

Giuseppe Sangiorgio, Ilenia Martina Pia Filannino, Giuseppe Migliorisi, Dafne Samantha Irene Bongiorno, Nicolò Musso, Grete Francesca Privitera, Gabriella Santuccio, Dario Leotta, Maddalena Calvo, Stefania Stefani

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Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuseppe Sangiorgio *Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Ilenia Martina Pia Filannino *Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Giuseppe MigliorisiU.O.C. Laboratory Analysis Unit, A.O. "G.F. Ingrassia", Palermo, Italy.
Dafne Samantha Irene BongiornoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Nicolò MussoAdvanced and Innovative Diagnostic Academy (A.I.D.A.) S.r.l., Spin-off of BRIT Research Center, University of Catania, Catania, Italy.
Grete Francesca PriviteraDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Gabriella SantuccioComplex Operational Unit of Hematology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
Dario LeottaComplex Operational Unit of Hematology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
Maddalena CalvoU.O.C. Laboratory Analysis II, A.O.U. Policlinico "G. Rodolico- San Marco", Catania, Italy.
Stefania StefaniDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vancomycin-resistant Methods: We conducted a retrospective study including 46 VRE from two Italian hospitals. Clinical and epidemiological data were collected, and isolates were characterized by antimicrobial susceptibility testing and whole-genome sequencing. Four representative isolates ( Results: The majority of isolates were Discussion: Our findings highlighted the convergence of antimicrobial resistance and virulence traits in VRE, alongside functional evidence of strain-dependent adhesion and secretion of cytotoxic metabolites. Elevated H

Indexed as

BacteremiaEnterococcus faecalisEnterococcus faeciumGram-Positive Bacterial InfectionsImmunocompromised HostVancomycin-Resistant EnterococciAdultAgedAnti-Bacterial AgentsBacterial AdhesionCaco-2 CellsEpithelial CellsFemaleGenome, BacterialGenomicsHumansAnti-Bacterial AgentsHydrogen PeroxideVirulence FactorsEnterococcus spp.host-pathogen interactionimmunocompromised hostmolecular characterizationwhole genome sequencing

Identifiers

PMID41477006
PMCPMC12748236

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.