ArticleInternational journal of endocrinology2025
Association Between FT4/FT3 Ratio and Short-Term Treatment Response in Differentiated Thyroid Cancer Patients.
Article in International journal of endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Return to Work and Employment Outcomes in Survivors of Differentiated Thyroid Cancer: A Systematic Review.Journal of occupational rehabilitation · 2026Pooled it
- Association Between FT4/FT3 Ratio and Short-Term Treatment Response in Differentiated Thyroid Cancer Patients.International journal of endocrinology · 2025Article
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5 authors.
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Abstract
Background: Thyroid cancer is the most common endocrine tumor, with its incidence increasing worldwide. Although differentiated thyroid cancer (DTC) generally has a good prognosis, some patients still experience recurrence or persistent lesions after initial treatment. This study aimed to explore the relationship between free thyroxine (FT4)/free triiodothyronine (FT3) ratio and short-term treatment response in patients with DTC. Methods: A retrospective analysis was conducted on 225 patients with DTC who received treatment at the Nuclear Medicine Department of Deyang People's Hospital from 2019 to 2022. All patients underwent total or subtotal thyroidectomy followed by radioactive iodine therapy. Clinical data and preoperative laboratory test results were collected, and multivariable logistic regression analysis was used to evaluate the association between the FT4/FT3 ratio and the short-term treatment response in DTC, as well as trend analysis and restricted cubic spline (RCS) evaluation for nonlinear relationships. Results: Among the 225 patients, 159 (70.7%) achieved an excellent response (ER). Compared to the non-ER group, the ER group had higher levels of FT4 ( Conclusion: The FT4/FT3 ratio is significantly associated with short-term treatment response in patients with DTC. A higher FT4/FT3 ratio may be an independent predictive factor for a favorable prognosis in DTC patients. Future studies should further investigate its mechanisms and potential clinical applications.
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