Evidence map›Paper›PMID 41476842›Full record

ArticleInternational journal of dentistry2025

The Impact of Acute and Chronic Stress and Cannabinoid Extract Injection on Orthodontic Tooth Movement: An Experimental Rat Model Study.

Amin Golshah, Mohammad Moslem Imani, Fatemeh Azizi, Farzad Rezaei, Navid Rezaei, Zohre Farhangian, Fatemeh Ghorbani, Nafiseh Nikkerdar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amin GolshahDepartment of Orthodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0002-8167-7632
Mohammad Moslem ImaniDepartment of Orthodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0002-3982-5216
Fatemeh AziziDepartment of Orthodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0003-4727-4706
Farzad RezaeiDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.
Navid RezaeiDepartment of Orthodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0002-6392-453X
Zohre FarhangianDepartment Operative of Dentistry, Faculty of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0002-4462-2616
Fatemeh GhorbaniStudent Research Committee, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0003-1908-8666
Nafiseh NikkerdarDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran, kums.ac.ir.ORCID https://orcid.org/0000-0002-2477-1761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Knowledge about the effects of medications and supplements on orthodontic tooth movement (OTM) is imperative for orthodontists. This study aimed to assess the effects of acute and chronic stress and cannabinoid extract (CE; marijuana) injection on OTM in rats. Materials and Methods: In this animal experimental study, 220 male Wistar rats were randomly assigned to 22 subgroups ( Results: OTM was significantly greater under chronic stress (0.23 ± 0.19 mm) than acute stress (0.21 ± 0.16 mm, Conclusion: Daily CE injection combined with acute and chronic stress significantly enhances OTM in rats, accompanied by increased osteoclastic activity, vascularization, and decreased bone density. Quantitative data and statistical significance provide robust evidence of these effects.

Indexed as

acute stresscannabinoid extractchronic stressorthodontic tooth movement

Identifiers

PMID41476842
PMCPMC12752900

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.