Evidence map›Paper›PMID 41476807›Full record

ArticleClinical case reports2026

Heads Down for Acute Stroke: Supine Position for Acute Large Vessel Occlusion in Ischemic Stroke.

Hassaan A Khan, Emmanuel J Thomas, Sufyan K Zackariya, Kate M Kelly, Saniya K Zackariya, Zenia Qasim, Manaal Buchh, Ameera S Khan, Hala K Ansari, Holly P Lankford and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Hassaan A KhanDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Emmanuel J ThomasDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Sufyan K ZackariyaIndiana University School of Medicine - South Bend South Bend Indiana USA.
Kate M KellyGeorge Washington University School of Medicine Washington DC USA.
Saniya K ZackariyaDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Zenia QasimDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Manaal BuchhDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Ameera S KhanDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Hala K AnsariDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Holly P LankfordDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Leigh K Van RynDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Caroline C HowellDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Mahmoud D Al-FadhlIndiana University School of Medicine - South Bend South Bend Indiana USA.
Marie Nour KaramIndiana University School of Medicine - South Bend South Bend Indiana USA.ORCID https://orcid.org/0009-0005-4112-0513
Anthony V ThomasIndiana University School of Medicine - South Bend South Bend Indiana USA.ORCID https://orcid.org/0000-0001-9520-9306
Rodolfo GonzalezIndiana University School of Medicine - South Bend South Bend Indiana USA.
Faisal S ShariffDepartment of Internal Medicine The University of Toledo Toledo Ohio USA.
Adeela M AlizaiMichiana Ophthalmology LLC Mishawaka Indiana USA.
Donald F ZimmerIndiana University School of Medicine - South Bend South Bend Indiana USA.
Mathew K MarseeDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.
Mark M WalshDepartment of Emergency and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA.ORCID https://orcid.org/0000-0002-5795-1144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case demonstrates that for large vessel occlusion strokes in the acute stage before surgical, pharmacologic, or radiologic intervention, supine positioning may be assumed because of the hemodynamic changes that can prevent and alleviate stroke, supporting the results of the ZerO Degree head positioning In Acute ischemiC stroke (ZODIAC) trial.

Indexed as

carotid artery thrombosiscollateral circulationischemic strokeophthalmic arterystents

Identifiers

PMID41476807
PMCPMC12753192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.