ArticleFrontiers in neurology2025
Predicting 90-day postoperative outcomes in spontaneous supratentorial intracerebral hemorrhage: a double-center study of clinical-radiomics integration using non-contrast CT.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the clinical utility of integrating baseline non-contrast computed tomography (NCCT) radiomics with clinical and surgical parameters for predicting 90-day postoperative functional outcomes in patients with spontaneous supratentorial intracerebral hemorrhage (sICH). Materials and methods: We retrospectively analyzed data from 220 patients with sICH who underwent surgical treatment from January 2022 to January 2025. Patients from Center 1 ( Results: Six independent clinical risk factors (age, hydrocephalus, brain herniation, hematoma location, hematoma volume, surgical duration) and three optimal radiomics features (Flatness, Least axis length, VolumeCC) were identified. The combined model achieved the highest area under the receiver operating characteristic curve values: 0.882 in the training cohort and 0.865 in the validation cohort, outperforming the clinical model (0.844, 0.830) and Radscore (0.769, 0.743). Conclusion: NCCT radiomics integrated with clinical parameters effectively predicts 90-day postoperative outcomes in sICH. The combined model, visualized as a nomogram, aids preoperative risk stratification and personalized treatment.
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