Evidence map›Paper›PMID 41476661›Full record

ReviewExploration (Beijing, China)2025

Multi-Energy Integrated Photocatalysis for Antitumor Therapy.

Li Zhang, Jun Liu, Yuxuan Xiong, Guangfu Liao, Yonggang Lv

Abstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Emerging copper-based hollow nanoplatforms for cancer treatment.International journal of pharmaceutics: X · 2026
    Review
  3. Article
  4. Article
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li ZhangState Key Laboratory of New Textile Materials and Advanced Processing Wuhan Textile University Wuhan P. R. China.ORCID https://orcid.org/0000-0002-3265-5699
Jun LiuState Key Laboratory of New Textile Materials and Advanced Processing Wuhan Textile University Wuhan P. R. China.
Yuxuan XiongDepartment of Chemistry The University of Chicago Chicago Illinois USA.
Guangfu LiaoCollege of Material Engineering Fujian Agriculture and Forestry University Fuzhou China.ORCID https://orcid.org/0000-0003-1299-8106
Yonggang LvState Key Laboratory of New Textile Materials and Advanced Processing Wuhan Textile University Wuhan P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photocatalysis has been recognized as a promising approach in cancer theranostics over the past years. To enhance therapeutic outcomes and overcome current limitations, significant attention has been directed toward the development of multi-energy integrated photocatalytic systems, particularly piezo-photocatalysts and photothermal-photocatalysts. Piezo-photocatalysis combines the piezoelectric effect with photocatalysis, offering superior efficiency, targeted action, and improved safety compared to traditional photocatalytic methods. By harnessing both mechanical and optical stimuli, this approach enables more precise and effective cancer therapies. On the other hand, photothermal-photocatalysis integrates heat induced by light with photocatalytic reactions, accelerating reaction rates and promoting the generation of reactive oxygen species. The synergistic interaction of heat and photocatalysis enhances tumor cell apoptosis more effectively than either modality alone. This review provides a systemic overview of the emerging multi-energy integrated photocatalytic strategies for cancer treatment. It begins with an exploration of the principles of piezo-photocatalysis and its potential to improve cancer therapies such as piezoelectric-enhanced single-modal photodynamic therapy (PDT), dual-modal sono-photodynamic therapy, and triple-modal hydrodynamic therapy/gas therapy (GT)/chemotherapy. Next, we delve into photothermal-photocatalysis and examine how its integration with additional treatment modalities, such as dual-modal photothermal/photocatalytic therapy (PTT/PCT) and PTT/PDT, can enhance therapeutic efficacy. Furthermore, we discuss more complex multi-modal treatments, including triple-modal PTT/PCT/chemotherapy, PTT/PCT/chemodynamic therapy (CDT), PTT/PCT/GT, PTT/PCT/immunotherapy (IT) and tetra-modal PTT/PCT/CDT/chemotherapy, PTT/PCT/CDT/ferroptosis therapy (FT), PTT/PCT/FT/IT, and PTT/PCT/GT/IT. Finally, we address the challenges and future directions in advancing these novel therapeutic paradigms. This review aims to provide a comprehensive resource for future research dedicated to advancing innovative multi-energy integrated photocatalytic systems in the field of cancer nanotheranostics.

Indexed as

cancer nanotheranosticsphotothermal‐photocatalystspiezo‐photocatalystsreactive oxygen

Identifiers

PMID41476661
PMCPMC12752655

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.