ReviewFrontiers in oncology2025
Addressing the cancer burden in LMICs: the potential of modulated electro-hyperthermia.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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6 authors.
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Abstract
Cancer in low- and middle-income countries (LMICs) is associated with late-stage diagnoses and poor survival, compounded by limited access to screening, diagnostic tools, and treatment. The high prevalence of HIV further complicates outcomes, especially in sub-Saharan Africa. Hyperthermia has emerged as a valuable adjunct to treatment in high-income countries, particularly for locally advanced cancers such as cervical and head and neck tumours, which are common in resource-constrained settings. Uptake of hyperthermia in LMICs has however been limited. A phase III randomised controlled trial in a South African public hospital demonstrated that modulated electro-hyperthermia (mEHT), a capacitively coupled heating technique, was feasible in this setting. The trial, the first to assess hyperthermia in Africa and to include HIV-positive participants, found that adding mEHT to chemoradiotherapy significantly improved 5-year disease-free survival (32% vs. 14%; HR:0.73; 95%CI:0.53-1.00;
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