Evidence map›Paper›PMID 41476560›Full record

ArticleACS omega2025

Highly Potent Phosphinic HIV‑1 Protease Inhibitors: Synthesis, In Vitro Evaluation, and Docking Studies.

Komal Hayat, Danwen Qiu, Yuanyuan Wang, Palmer Sivoko Imbenzi, Faez Iqbal Khan, Magdalini Matziari

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Komal HayatDepartment of Chemistry and Materials Science, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.ORCID https://orcid.org/0000-0003-0682-648X
Danwen QiuDepartment of Chemistry and Materials Science, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.ORCID https://orcid.org/0009-0007-2405-3499
Yuanyuan WangDepartment of Biosciences and Bioinformatics, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.
Palmer Sivoko ImbenziDepartment of Chemistry and Materials Science, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.ORCID https://orcid.org/0000-0002-1820-7080
Faez Iqbal KhanDepartment of Biosciences and Bioinformatics, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.
Magdalini MatziariDepartment of Chemistry and Materials Science, School of Science, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, SIP, Suzhou, Jiangsu Province 215123, P. R. China.ORCID https://orcid.org/0000-0003-0324-0934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the search for effective HIV-1 protease inhibitors, the design of symmetrical phosphinic pseudopeptides derived from a dual addition of hypophosphorous acid to acrylates (

Identifiers

PMID41476560
PMCPMC12750381

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.