Evidence map›Paper›PMID 41476487›Full record

ArticleACS omega2025

Cytosporone B Affects ATP Production of

Augusto Leonardo Dos Santos, Maiara Amaral, Erica V de Castro Levatti, Maiara Romanelli, Marcelo J Pena Ferreira, Andre G Tempone, Patrícia Sartorelli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Augusto Leonardo Dos SantosInstituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo (Unifesp), Campus Diadema, Diadema, São Paulo 09972-270, Brazil.ORCID https://orcid.org/0000-0003-1590-8145
Maiara AmaralPathophysiology Laboratory, Instituto Butantan, São Paulo, São Paulo 05503-900, Brazil.
Erica V de Castro LevattiPathophysiology Laboratory, Instituto Butantan, São Paulo, São Paulo 05503-900, Brazil.
Maiara RomanelliPathophysiology Laboratory, Instituto Butantan, São Paulo, São Paulo 05503-900, Brazil.
Marcelo J Pena FerreiraBotany Department, Institute of Biosciences, University of São Paulo, São Paulo 05508-090, Brazil.ORCID https://orcid.org/0000-0003-1877-1762
Andre G TemponePathophysiology Laboratory, Instituto Butantan, São Paulo, São Paulo 05503-900, Brazil.ORCID https://orcid.org/0000-0003-2559-7344
Patrícia SartorelliInstituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo (Unifesp), Campus Diadema, Diadema, São Paulo 09972-270, Brazil.ORCID https://orcid.org/0000-0002-1624-8145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease is a neglected parasitic infection spreading worldwide and affecting 8-10 million people, with 14,000 deaths. The treatment is limited to two toxicity nitroheterocycle drugs, approved more than 50 years ago. Considering the urgent need for new therapies, secondary metabolites isolated from endophytic fungi may represent a useful source of bioactive molecules with antiparasitic activity, as described in the literature. In this study, we investigated the anti-

Identifiers

PMID41476487
PMCPMC12750222

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.