Evidence map›Paper›PMID 41476186›Full record

Trial reportScientific reports2025

Clinical outcomes of intra-articular corticosteroid injection vs. multimodal physiotherapy in patients with frozen shoulder in short term: a randomized clinical trial.

Mohammad Ali Zare, Mohammad Hosein Ebrahimzadeh, Ali Moradi, Afsaneh Zeinalzadeh, Salman Nazary-Moghadam

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Ali ZareDepartment of Physical Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Hosein EbrahimzadehOrthopaedics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali MoradiOrthopaedics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Afsaneh ZeinalzadehDepartment of Physical Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Salman Nazary-MoghadamDepartment of Physical Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran. Nazaryms@mums.ac.ir.

Funding

Mashhad University of Medical Sciences 4001264
6 · The paper itself

Abstract

This study aimed to compare the short-term effects of multimodal physiotherapy (MPT) with intra-articular corticosteroid injection (IAI) on pain, disability, effectiveness of treatment, and passive range of motion in patients with frozen shoulder. Randomized Controlled Trial. University Hospital. Patients diagnosed with frozen shoulder with at least 50% passive range of motion (PROM) limitation. Forty-eight patients were allocated into two groups: Group A: MPT and Group B: IAI. After allocation, all patients received a prescription of a comprehensive home exercise pamphlet (HEP) and were instructed to perform them for six weeks. Pain ((visual analogue scale (VAS), shoulder pain and disability index (SPADI)), disability (SPADI), and PROM for abduction, external rotation, and scaption were recorded at the baseline and 6 weeks after randomization. The effectiveness of treatment (global rating scale (GRC)) was recorded 6 weeks after randomization. Pain (VAS) and (SPADI), disability (SPADI), and passive range of motion (PROM) significantly improved after both treatments (p < 001). The effect size of MPT was larger than IAI for all outcomes. Notably, significant positive differences were observed in internal rotation PROM (p = 0.036, effect size (ES) = 0.627) and the disability section of the GRC scale (p = 0.005), indicating that MPT was more effective. However, in VAS, SPADI (total), GRC (pain), external rotation, abduction, and scaption PROM, the difference between the treatment groups was not statistically significant. MPT and IAI are both effective short-term interventions. The stronger effect and specific superior outcomes of MPT are promising, but the limited sample size precludes definitive conclusions regarding superiority. Larger trials are warranted to confirm these findings.

Indexed as

Adrenal Cortex HormonesBursitisPhysical Therapy ModalitiesAdultAgedCombined Modality TherapyFemaleHumansInjections, Intra-ArticularMaleMiddle AgedPain MeasurementRange of Motion, ArticularTreatment OutcomeAdrenal Cortex HormonesDisabilityFrozen shoulderIntra-articular injectionMobilizationPainProprioceptive neuromuscular facilitation

Identifiers

PMID41476186
PMCPMC12848112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.