Evidence map›Paper›PMID 41475840›Full record

ArticleRMD open2025

Patient-tailored training programme on cardiorespiratory fitness, trunk strength and mobility leads to significantly better outcomes in individuals with axial spondyloarthritis.

Sophie De Mits, Tine Willems, Patrick Calders, Lieven Danneels, Gaëlle Varkas, Filip Van den Bosch, Dirk Elewaut, Philippe Carron

Abstract read
In one paragraph

Article in RMD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sophie De Mits *Rheumatology, University Hospital Ghent, Ghent, Flanders, Belgium sophie.demits@uzgent.be.ORCID 0000-0003-4541-9895
Tine Willems *Rehabilitation Sciences, Ghent University, Ghent, Flanders, Belgium.ORCID 0000-0001-8331-9700
Patrick CaldersRehabilitation Sciences, Ghent University, Ghent, Flanders, Belgium.ORCID 0000-0001-6327-8155
Lieven DanneelsRehabilitation Sciences, Ghent University, Ghent, Flanders, Belgium.ORCID 0000-0002-3030-2697
Gaëlle VarkasRheumatology, University Hospital Ghent, Ghent, Flanders, Belgium.ORCID 0000-0001-7606-9256
Filip Van den BoschRheumatology, University Hospital Ghent, Ghent, Flanders, Belgium.ORCID 0000-0002-3561-5932
Dirk ElewautRheumatology, University Hospital Ghent, Ghent, Flanders, Belgium.ORCID 0000-0002-7468-974X
Philippe CarronRheumatology, University Hospital Ghent, Ghent, Flanders, Belgium.ORCID 0000-0001-9254-6171

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAxial spondyloarthritis (axSpA) impairs trunk strength, mobility and cardiorespiratory fitness. Despite exercise being a key treatment, few studies have examined a combined trunk mobility, strength and cardiorespiratory training programme. This prospective interventional study assessed the benefits of a personalised training programme based on baseline physical tests.

methodsPeople with axSpA underwent cardiopulmonary exercise testing (CPET) and trunk strength/mobility assessments using the David Back Concept (DBC) devices. Strength and mobility deficits were calculated, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI) and chest expansion (CE) were recorded pre-intervention and post-intervention. The 8-week programme included two sessions per week of cardiorespiratory training (based on ventilatory threshold, heart rate monitored via a Polar device), followed by resistance/mobility exercises on DBC devices. Training intensity was tailored to each individual's one-repetition-maximum and range of motion at baseline. Post-intervention, CPET and DBC tests were repeated. Changes were analysed using linear mixed models.

results30 individuals with axSpA (14 males/16 females, age 42±11.2 years, BASDAI 3.5±2.1, BASFI 2.8±2.2, BASMI 2.0±1.1, CE 4.5±2.0 cm) participated; two were lost to follow-up. Strength increased by 14.1% (p<0.001) and mobility by 14.9% (p<0.001). Significant improvements occurred in oxygen pulse (p=0.004), ventilatory efficiency (p<0.001), anaerobic threshold (p=0.002) and mechanical efficiency (p=0.021). BASDAI (2.9±2.2, p=0.021) and CE (5.0±2.1, p=0.020) improved significantly; BASMI (1.8±1.0, p=0.053) showed borderline improvement, while BASFI remained unchanged (2.4±2.1, p=0.092).

conclusionA combined, tailored and baseline-guided training programme significantly enhanced cardiorespiratory fitness, trunk strength and trunk mobility in individuals with axSpA, supporting individualised exercise interventions to improve outcomes and reduce functional limitations.

Indexed as

Axial SpondyloarthritisCardiorespiratory FitnessExercise TherapyMuscle StrengthAdultExercise TestFemaleHumansMaleMiddle AgedProspective StudiesRange of Motion, ArticularResistance TrainingTreatment OutcomeAxial SpondyloarthritisPhysical Therapy ModalitiesRehabilitation

Identifiers

PMID41475840
PMCPMC12766781

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.