Evidence map›Paper›PMID 41475822›Full record

Observational studyBMJ open2025

Factors Associated with Retention in Routine Well-Care Visits Among Children of Adolescent Mothers Living With and Without HIV: A Community-Based Study in the Eastern Cape, South Africa.

Camille Wittesaele, Elona Toska, Lucie D Cluver, Helen A Weiss, Aoife M Doyle

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camille WittesaeleInternational Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK cwittesaele@itg.be.ORCID http://orcid.org/0000-0001-8828-5685
Elona ToskaDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-3800-3173
Lucie D CluverDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.
Helen A WeissInternational Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0003-3547-7936
Aoife M DoyleInternational Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0002-3305-7738

Funding

Undetectable and Untransmittable: reducing HIV transmission among young women living with HIV, their partners and children in South AfricaK43TW011434 · FIC · UNIVERSITY OF CAPE TOWN · PI TOSKA, ELONA · 2019 to 2023
$720k
FIC NIH HHS K43 TW011434
6 · The paper itself

Abstract

objectiveTo describe well-care visit attendance among children of adolescent mothers living with HIV and HIV-negative adolescent mothers and identify factors associated with optimal retention in the well-care visit schedule up to 18 months. DESIGN, SETTING,

participantsCross-sectional data were used from a community-based observational cohort study of adolescent mothers (10-19 years; n=481) and their children (≥19 months old; n=502) in the Eastern Cape, South Africa. OUTCOME: Optimal well-care visit retention up to 18 months was defined as attending visits within 4 weeks of the recommended child age, attending the 18-month visit and missing no more than one scheduled visit.

resultsAttendance was highest at the 6-week visit (88.4%; 95% confidence interval (CI) 85.6% to 91.3%) and lowest at the 18-month visit (58.0%, 95% CI 53.6% to 62.3%). About one-third (36.1%; 95% CI 31.8% to 40.3%) of children were retained to 18 months. Retention was highest among children living in rural vs urban areas (adjusted odds ratio (aOR)=2.01, 95% CI 1.32 to 3.06), those born to mothers whose highest education at pregnancy was secondary versus primary school (aOR=2.73, 95% CI 1.60 to 4.65), born via caesarean section vs vaginal birth (aOR=1.65, 95% CI 1.05 to 2.60) and living closer to the clinic (aOR=0.52, 95% CI 0.28 to 0.96 for long vs short distance). There was weak evidence that retention was lower among children of mothers living with HIV (aOR=0.64, 95% CI 0.40 to 1.02) and higher among food-secure children (aOR=2.18, 95% CI 0.96 to 4.96) and those receiving the child support grant (aOR=1.71, 95% CI 0.92 to 3.16).

conclusionsUniversal interventions are needed for retention beyond the neonatal period for children of adolescent mothers living with HIV and HIV-negative adolescent mothers. Interventions must address structural barriers, especially for adolescent mothers with primary education and in urban areas. Future research should examine the underlying mechanisms linking mode of delivery with well-care retention.

Indexed as

HIV InfectionsPregnancy in AdolescenceRetention in CareAdolescentAdultChildCross-Sectional StudiesFemaleHumansInfantInfectious Disease Transmission, VerticalMaleMothersPregnancySouth AfricaYoung AdultCommunity child healthHealth Services AccessibilityPerson-Centered CarePreventive Health ServicesPrimary Health Care

Identifiers

PMID41475822
PMCPMC12766768

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.