Evidence map›Paper›PMID 41475497›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2026

Role of social determinants and outcomes of patients with alcohol-associated liver disease referred for early liver transplantation: A multicenter analysis.

Bima J Hasjim, Anjana Rajan, Nivetha Saravanan, Weiyu Wu, Allison J Kwong, Kawthar Mohamed, Nicholas Lim, Katherine M Cooper, Deepika Devuni, Kevin Wang and 4 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bima J HasjimDepartment of Surgery, University of California, Irvine, Orange, California, USA.
Anjana RajanDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Nivetha SaravananDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Weiyu WuDivision of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, California, USA; Stanford Transplant Outcomes Research Center, Stanford, California, USA.
Allison J KwongDivision of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, California, USA; Stanford Transplant Outcomes Research Center, Stanford, California, USA.
Kawthar MohamedDivision of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, Minnesota, USA.
Nicholas LimDivision of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, Minnesota, USA; Division of Gastroenterology and Hepatology, University of Rochester, Rochester, New York, USA; Transplant Institute, University of Rochester, Rochester, New York, USA.
Katherine M CooperDivision of Gastroenterology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Deepika DevuniDivision of Gastroenterology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Kevin WangDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Hersh ShroffDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Kaleb TesfaiDivision of Gastroenterology and Hepatology, Department of Medicine, University of California San Diego, San Diego, California, USA.
Veeral H AjmeraDivision of Gastroenterology and Hepatology, Department of Medicine, University of California San Diego, San Diego, California, USA.
Amanda CheungDivision of Gastroenterology and Hepatology, Northwestern University, Chicago, Illinois, USA. Electronic address: amanda.cheung@nm.org.

Funding

Defining Phenotypes of Alcohol-Associated Liver Disease with Acute Hepatic DecompensationK23AA029197 · NIAAA · STANFORD UNIVERSITY · PI KWONG, ALLISON · 2021 to 2025
$1.0M
NIAAA NIH HHS K23 AA029197
6 · The paper itself

Abstract

Liver transplantation (LT) before 6 months of sobriety (early LT) for alcohol-associated liver disease (ALD) improves survival with acceptable relapse rates. Patients with disadvantaged social determinants of health (SDOH) may have disparate access to early LT and outcomes, though it is unclear. This was a retrospective study of the Recovery, Survival, and Outcomes in ALD consortium, which includes patients with ALD referred for early LT across 6 centers in the United States from 2018 to 2021. The area deprivation index (ADI) estimated area-level SDOH, and patients were stratified into low (ADI <50) and high ADI (ADI ≥50). Six hundred seven patients were evaluated for early LT; 25% resided in high ADI areas, and 73.8% in low ADI areas. Those in high ADI areas were more likely to be of underrepresented race/ethnicity and traveled further to LT centers (P < .001). After adjusting for clinicodemographic covariates, increasing ADI were associated with higher risks of waitlist (subdistribution hazard ratio [sHR] 1.01, 95% confidence interval [CI], 1.01-1.03) and post-LT (HR 1.02, 95% CI, 1.00-1.05) mortality, though LT receipt (sHR 1.00; 95% CI, 0.99-1.01) and risks of relapse (HR, 1.00; 95% CI, 0.99-1.01) were similar. Satisfactory ALD-related endpoints may be achieved among select candidates, although patients who reside in vulnerable SDOH areas have lower pre- and post-LT survival, suggesting disparate LT care.

Indexed as

Liver Diseases, AlcoholicLiver TransplantationReferral and ConsultationSocial Determinants of HealthAdultFemaleFollow-Up StudiesGraft SurvivalHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSurvival RateUnited Statesalcohol-related liver diseaseearly liver transplantationsocial determinants of healthsurvivalwaitlisting

Identifiers

PMID41475497
PMCPMC13403990

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.