Evidence map›Paper›PMID 41475378›Full record

ArticlemSystems2026

The NIAID Discovery Portal: a unified search engine for infectious and immune-mediated disease datasets.

Ginger Tsueng, Emily Bullen, Candice Czech, Dylan Welzel, Leandro Collares, Jason Lin, Everaldo Rodolpho, Zubair Qazi, Nichollette Acosta, Lisa M Mayer and 11 more

Abstract read
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ginger TsuengThe Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0001-9536-9115
Emily BullenThe Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0003-2488-0850
Candice CzechThe Scripps Research Institute, La Jolla, California, USA.
Dylan WelzelThe Scripps Research Institute, La Jolla, California, USA.
Leandro CollaresThe Scripps Research Institute, La Jolla, California, USA.
Jason LinThe Scripps Research Institute, La Jolla, California, USA.
Everaldo RodolphoThe Scripps Research Institute, La Jolla, California, USA.
Zubair QaziThe Scripps Research Institute, La Jolla, California, USA.
Nichollette AcostaThe Scripps Research Institute, La Jolla, California, USA.
Lisa M MayerOffice of Data Science and Emerging Technologies, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA.
Sudha VenkatachariNational Cancer Institute, Rockville, Maryland, USA.
Zorana Mitrović VučičevićVelsera, Charlestown, Maryland, USA.
Poromendro N BurmanVelsera, Charlestown, Maryland, USA.
Deepti JainVelsera, Charlestown, Maryland, USA.
Jack DiGiovannaVelsera, Charlestown, Maryland, USA.
Maria GiovanniNational Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA.
Asiyah LinOffice of Data Science and Emerging Technologies, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA.
Wilbert Van PanhuisOffice of Data Science and Emerging Technologies, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA.
Laura D HughesThe Scripps Research Institute, La Jolla, California, USA.
Andrew I SuThe Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0002-9859-4104
Chunlei WuThe Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0002-2629-6124

Funding

Frederick National Laboratory for Cancer Research 75N91020F00022
6 · The paper itself

Abstract

The National Institute of Allergy and Infectious Diseases (NIAID) Data Ecosystem Discovery Portal (https://data.niaid.nih.gov) provides a unified search interface for over 4 million data sets relevant to infectious and immune-mediated disease (IID) research. Integrating metadata from domain-specific and generalist repositories, the Portal enables researchers to identify and access data sets using user-friendly filters or advanced queries, without requiring technical expertise. The Portal supports discovery of a wide range of resources, including epidemiological, clinical, and multi-omic data sets and is designed to accommodate exploratory browsing and precise searches. The Portal provides filters, prebuilt queries, and data set collections to simplify the discovery process for users. The Portal additionally provides documentation and an API for programmatic access to harmonized metadata. By easing access barriers to important biomedical data sets, the NIAID Data Ecosystem Discovery Portal serves as an entry point for researchers working to understand, diagnose, or treat IID.IMPORTANCEValuable data sets are often overlooked because they are difficult to locate. The NIAID Data Ecosystem Discovery Portal fills this gap by providing a centralized, searchable interface that empowers users with varying levels of technical expertise to find and reuse data. By standardizing key metadata fields and harmonizing heterogeneous formats, the Portal improves data findability, accessibility, and reusability. This resource supports hypothesis generation, comparative analysis, and secondary use of public data by the IID research community, including those funded by NIAID. The Portal supports data sharing by standardizing metadata and linking to source repositories and maximizes the impact of public investment in research data by supporting scientific advancement via secondary use.

Indexed as

Communicable DiseasesDatabases, FactualImmune System DiseasesSearch EngineHumansMetadataNational Institute of Allergy and Infectious Diseases (U.S.)United Statesdata discoverydata reuseFAIR dataimmunologyinfectious diseasemetadata harmonizationresource report

Identifiers

PMID41475378
PMCPMC12911352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.