Evidence map›Paper›PMID 41474384›Full record

ArticleThe Journal of physiology2026

Kidney disease impairs tendon function in rats.

Christopher M T Hayden, Natalie K Gilmore, Benjamin Osipov, Sarah E Brashear, Marc Gorge, Kuang-Yu Jen, Lucas R Smith, Blaine A Christiansen, Baback Roshanravan, Keith Baar

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Christopher M T HaydenMolecular Cellular and Integrative Physiology Graduate Group, University of California Davis, Davis, California, USA.
Natalie K GilmoreMolecular Cellular and Integrative Physiology Graduate Group, University of California Davis, Davis, California, USA.ORCID 0000-0001-8881-9157
Benjamin OsipovDepartment of Orthopaedic Surgery, University of California Davis Health, Sacramento, California, USA.
Sarah E BrashearDepartment of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, California, USA.ORCID 0000-0003-4601-3520
Marc GorgeDepartment of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, California, USA.
Kuang-Yu JenDepartment of Pathology and Laboratory Medicine, University of California Davis Health, Sacramento, California, USA.ORCID 0000-0003-2815-5912
Lucas R SmithDepartment of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, California, USA.ORCID 0000-0002-7610-4231
Blaine A ChristiansenDepartment of Orthopaedic Surgery, University of California Davis Health, Sacramento, California, USA.
Baback RoshanravanDepartment of Medicine, Division of Nephrology, University of California Davis Health, California, Sacramento, USA.
Keith BaarMolecular Cellular and Integrative Physiology Graduate Group, University of California Davis, Davis, California, USA.ORCID 0000-0001-9337-6186

Funding

NRSA Training CoreTL1DK139565 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PHILIP A BEACHY, Chi-yuan Hsu · 2023 to 2026
$5.1M
Training Program in PharmacologyT32GM144303 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Donald M Bers, JOHANNES W HELL · 2022 to 2026
$2.1M
NIDDK NIH HHS TL1 DK139565NIGMS NIH HHS T32 GM144303
6 · The paper itself

Abstract

Spontaneous tendon rupture occurs in a concerning number of individuals with chronic kidney disease (CKD); however almost no data exist regarding CKD-related tendon pathology. Given that tendon ruptures have a significant impact on health and well-being we sought to determine whether tendon mechanics are altered by kidney disease in an established rat model of CKD. Male and female Sprague-Dawley rats (age = 8 weeks) were equally divided into a control group (CON, n = 16) and a group fed a diet containing 0.25% adenine to induce kidney disease (

Indexed as

Achilles TendonRenal Insufficiency, ChronicTendonsAnimalsBiomechanical PhenomenaFemaleMaleRatsRats, Sprague-DawleyTensile Strengthadeninebone–mineral disordermechanicsmusclerupture

Identifiers

PMID41474384
PMCPMC12871929

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.