Evidence map›Paper›PMID 41474008›Full record

ArticleCancers2025

RETRACTED: Gravina et al. The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models.

Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale, Loredana Cristiano, Stefano Martellucci, Francesco Marampon, Vincenzo Mattei and 6 more

Abstract readRetraction Notice
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Giovanni Luca GravinaDivision of Radiation Oncology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.
Andrea ManciniLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.ORCID 0009-0005-0327-487X
Alessandro ColapietroLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.
Simona Delle MonacheLaboratory of cellular pathology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio 1 (Coppito II), 67100 L'Aquila, Italy.ORCID 0000-0002-8153-915X
Roberta SferraLaboratory of Human Anatomy; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.
Flora VitaleLaboratory of Neurophysiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.
Loredana CristianoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.ORCID 0000-0002-0539-0736
Stefano MartellucciLaboratory of cellular pathology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio 1 (Coppito II), 67100 L'Aquila, Italy.ORCID 0000-0002-3952-3162
Francesco MaramponDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Vincenzo MatteiLaboratory of Experimental Medicine and Environmental Pathology, University Hub "Sabina Universitas", 02100 Rieti, Italy.ORCID 0000-0003-4677-088X
Filip BeirinckxGalapagos NV, Industriepark Mechelen Noord, General De Wittelaan L11 A3, 2880 Mechelen, Belgium.
Philippe PujuguetGalapagos SASU, 102 avenue Gaston Roussel, 93230 Romainville, France.
Laurent SaniereGalapagos SASU, 102 avenue Gaston Roussel, 93230 Romainville, France.
Giocondo LorenzonGalapagos NV, Industriepark Mechelen Noord, General De Wittelaan L11 A3, 2880 Mechelen, Belgium.
Ellen van der AarGalapagos NV, Industriepark Mechelen Noord, General De Wittelaan L11 A3, 2880 Mechelen, Belgium.
Claudio FestucciaLaboratory of Radiobiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio (Coppito II), 67100 L'Aquila, Italy.ORCID 0000-0002-3463-6475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The journal retracts the article, "The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models" [...].

Identifiers

PMID41474008
PMCPMC12754618

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.