ArticleEuropean journal of obstetrics & gynecology and reproductive biology: X2025
The effect of curcumin capsule on the severity and duration of primary dysmenorrhea among students: A triple-blind randomized controlled trial in the West of Iran.
Article in European journal of obstetrics & gynecology and reproductive biology: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: The present study was conducted to evaluate the efficacy of curcumin capsules on the severity and duration of primary dysmenorrhea. Methods: A randomized controlled trial conducted among female students at Hamadan University of Medical Sciences who met predetermined inclusion criteria in 2024 at 34 participants per group. In the intervention group, participants received curcumin capsules containing 500 mg of curcumin. These capsules were ingested once daily over the course of two menstrual cycles. The control group was administered placebo capsules, which contained 500 mg of starch, with the method of administration mirroring that of the intervention group. Data collection tools were including demographic characteristics questionnaire, visual pain ruler, pain duration and multidimensional verbal scale. Results: after the intervention, a significant difference emerged (P < 0.001). In the intervention group, dysmenorrhea severity decreased significantly from a mean of 6.5-4.53 in the first menstrual cycle and further reduced to 3.44 in the second cycle. In contrast, the control group showed no significant change. The intervention group's improvement was consistent across both cycles, highlighting the effectiveness of the intervention in reducing dysmenorrhea severity (P < 0.001). Conclusion: curcumin capsules can be used as an effective and low-risk complementary treatment for reducing the severity and duration of primary dysmenorrhea.
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