Evidence map›Paper›PMID 41473848›Full record

ArticleJournal of experimental orthopaedics2025

Therapeutic ultrasound and passive mobilisation improve motor function and reduce inflammation in skeletal muscle of immobilised Wistar rats.

Fernanda Teixeira Furlan Chico, Ana Caroline Barbosa Retameiro, Aline Reginato, Rafaela Rambo Bremm, Bruna Menegat, Mustafa Munir Mustafa Dahleh, Marina Prigol, Gustavo Petri Guerra, Gladson Ricardo Flor Bertolini, Lucinéia de Fátima Chasko Ribeiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernanda Teixeira Furlan ChicoUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.
Ana Caroline Barbosa RetameiroUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.
Aline ReginatoUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.
Rafaela Rambo BremmUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.
Bruna MenegatUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.
Mustafa Munir Mustafa DahlehUniversidade Federal do Pampa Laboratory for Pharmacological and Toxicological Evaluations Applied to Bioactive Molecules Itaqui Rio Grande do Sul Brazil.
Marina PrigolUniversidade Federal do Pampa Laboratory for Pharmacological and Toxicological Evaluations Applied to Bioactive Molecules Itaqui Rio Grande do Sul Brazil.
Gustavo Petri GuerraUniversidade Federal do Pampa Laboratory for Pharmacological and Toxicological Evaluations Applied to Bioactive Molecules Itaqui Rio Grande do Sul Brazil.
Gladson Ricardo Flor BertoliniUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.ORCID https://orcid.org/0000-0003-0565-2019
Lucinéia de Fátima Chasko RibeiroUniversidade Estadual do Oeste do Paraná Center of Biological and Health Sciences Cascavel Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Here we analysed the effects of treatment with therapeutic ultrasound, passive mobilisation and their synergically effects on hind paw' functionality, histomorphometric and immunological aspects in the musculoskeletal tissue in an experimental immobilisation model. Methods: Forty male Wistar rats, aged 10 weeks were divided into ( Results: Histomorphometry revealed hypotrophy and fibrosis in the muscular tissue, with changes in the muscle fibres, connective tissue and muscle spindles ( Conclusion: Treatments synergistically restored motor function, histomorphometric integrity, and immunological balance in the musculoskeletal tissue of the rats after immobilisation. This may indicate that in humans there should be integration of therapies in post-immobilisation periods. Level of Evidence: N/A.

Indexed as

comparative histologyhindlimb immobilisationmorphologyultrasonic therapywestern immunoblotting

Identifiers

PMID41473848
PMCPMC12745041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.