Evidence map›Paper›PMID 41473846›Full record

ArticleJournal of experimental orthopaedics2025

Postoperative analgesia in total knee arthroplasty for posttraumatic arthritis: A randomised controlled trial comparing patient-controlled intravenous analgesia, continuous femoral/sciatic nerve block and continuous local infiltration analgesia.

Bastian Mester, Tobias Ohmann, Christine Seelmann, Anne Terschluse, Claas Güthoff, Christian Gerach, Nikolaus Brinkmann, Marcel Dudda

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bastian MesterDepartment of Trauma, Hand and Reconstructive Surgery University Hospital Essen Essen Germany.ORCID https://orcid.org/0000-0003-2125-7078
Tobias OhmannResearch Department BG-Klinikum Duisburg Duisburg Germany.ORCID https://orcid.org/0000-0003-1762-2765
Christine SeelmannResearch Department BG-Klinikum Duisburg Duisburg Germany.ORCID https://orcid.org/0000-0002-4242-6646
Anne TerschluseUniversity of Duisburg-Essen Universitätsstraße 2 Essen Germany.
Claas GüthoffCentre for Clinical Research BG-Klinikum Unfallkrankenhaus Berlin Berlin Germany.ORCID https://orcid.org/0000-0002-9984-6908
Christian GerachDepartment of Anesthesiology and Intensive Care Medicine BG-Klinikum Duisburg Duisburg Germany.
Nikolaus BrinkmannDepartment of Orthopaedics and Trauma Surgery, BG-Klinikum Duisburg University of Duisburg-Essen Duisburg Germany.
Marcel DuddaDepartment of Trauma, Hand and Reconstructive Surgery University Hospital Essen Essen Germany.ORCID https://orcid.org/0000-0001-6641-5506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Postoperative pain remains a major obstacle to early mobilisation following total knee arthroplasty (TKA) and is particularly challenging in patients with posttraumatic arthritis due to prior injury, scarring, and complex surgeries. While various analgesic strategies have been evaluated in degenerative TKA, evidence in posttraumatic cases is lacking. This study is the first to compare patient-controlled intravenous analgesia (PCIA), continuous femoral/sciatic nerve block (cFNB/cSNB), and continuous local infiltration analgesia (cLIA) in this specific population. Methods: In this prospective, monocentric, randomised controlled trial, 92 patients undergoing TKA for posttraumatic arthritis were allocated to PCIA ( Results: At t1, patients in cFNB/cSNB reported significantly lower pain scores compared to cLIA ( Conclusions: In patients undergoing TKA for posttraumatic arthritis, cFNB/cSNB provided superior early postoperative pain control and functional recovery compared to PCIA and cLIA. The findings suggest that standard fast-track protocols may not be fully applicable in this complex patient population, highlighting the need for individualised analgesic strategies. Level of Evidence: Level I.

Indexed as

local infiltration analgesianerve blockpain managementposttraumatic arthritistotal knee arthroplasty

Identifiers

PMID41473846
PMCPMC12745048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.