Evidence map›Paper›PMID 41473821›Full record

ArticleCase reports in oncological medicine2025

An Aggressive Case of Thymic Lymphoepithelial Carcinoma Complicated by Cytokine Release Syndrome: A Case Report.

Louis G Filipiak, Nyembezi L Dhliwayo, Koosha Paydary

Abstract read
In one paragraph

Article in Case reports in oncological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louis G FilipiakRush University Medical Center, Chicago, Illinois, USA, rush.edu.ORCID https://orcid.org/0009-0001-2635-2691
Nyembezi L DhliwayoRush University Medical Center, Chicago, Illinois, USA, rush.edu.
Koosha PaydaryRush University Medical Center, Chicago, Illinois, USA, rush.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic lymphoepithelial carcinomas (TLECs) are a rare primary thymic cancer best described by lymphoplasmacytic infiltration of the thymic stroma. Though only accounting for 1.3%-6% of thymic carcinomas, the distribution of TLECs is bimodal, peaking around ages 14 and 48 and affecting males to females in a 2:1 ratio. Due to their rarity and aggressive nature, they often present at later stages and can be primarily treated with a combination of chemotherapy and radiation. While several paraneoplastic syndromes have been reported with TLECs, cytokine release syndrome (CRS) has been observed in several cases. This particular case illustrates a metastatic TLEC patient that was treated with chemotherapy and complicated by CRS.

Identifiers

PMID41473821
PMCPMC12747051

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.