Evidence map›Paper›PMID 41473817›Full record

ArticleCase reports in oncological medicine2025

A Novel Approach for Stereotactic Radiosurgery of Multiple Brain Metastasis in a Patient With Poor Performance Status: A Case Report.

Arad Iranmehr, Shakiba Sheikholeslami, Nooshin Banaee, Mohammad Shirani, Mostafa Farzin, Fatemeh Jafari

Abstract read
In one paragraph

Article in Case reports in oncological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arad IranmehrNeurosurgery Department, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
Shakiba SheikholeslamiRadiation Oncology Department, Cancer Institute, Imam-Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
Nooshin BanaeeDepartment of Nuclear Engineering, CT.C, Islamic Azad University, Tehran, Iran, azad.ac.ir.
Mohammad ShiraniNeurosurgery Department, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
Mostafa FarzinGamma Knife Center, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
Fatemeh JafariGamma Knife Center, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-9862-6524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brain metastases are the most common malignant intracranial tumors in adults. The management of patients with poor performance status and multiple brain metastases remains controversial, with guidelines generally recommending palliative care in such cases. Stereotactic radiosurgery has been debated for this group of patients, particularly those with multiple lesions. Case Presentation: We present a case of an Iranian patient with metastatic non-small cell lung cancer (NSCLC) who had previously undergone whole-brain irradiation (WBRT). The patient was referred due to the progression of multiple brain lesions. In response, we administered two separate courses of fractionated stereotactic radiation therapy (FSRT) to treat these brain masses. The patient's neurological symptoms showed significant improvement following the treatment. Conclusions: This case suggests that stereotactic radiation therapy can be considered for patients with poor performance status, regardless of the number of brain metastases. It may stabilize or improve neurological deficits and enhance the patient's quality of life, even if its effect on overall survival is uncertain. Additionally, treating the lesions in two separate courses may reduce treatment time and facilitate better repair of normal brain tissue.

Indexed as

brain metastasesradiosurgerystereotactic radiosurgery

Identifiers

PMID41473817
PMCPMC12747105

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.