SynthesisFrontiers in cellular and infection microbiology2025
Meta-analysis of the prevalence of
Synthesis in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background: Methods: A systematic review and meta-analysis was performed in accordance with PRISMA guidelines. Six databases (PubMed, Web of Science, ScienceDirect, CNKI, VIP, Wanfang) were searched up to April 2025. Eligible studies reported mosquito infection rates with defined sample size, location, and diagnostic method. Study quality was appraised using the Joanna Briggs Institute checklist for prevalence studies. Statistical synthesis was conducted in R (v4.1.2) using random-effects models. Subgroup analyses and meta-regression explored heterogeneity by region, mosquito genus, and detection method. Results: Eighteen studies covering 160,423 mosquitoes from 10 countries were included. The pooled infection prevalence was 0.7% (95% CI [0.3-1.7]). Rates were highest in Asia (3.0%, 95% CI [0.0-10.7]), in Conclusions: Filarial infections in mosquitoes remain widespread, with clear regional and methodological variability. Strengthened mosquito-based xenomonitoring, particularly using molecular diagnostic approaches, will be essential to accelerate progress toward global lymphatic filariasis elimination by 2030.
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