Evidence map›Paper›PMID 41473694›Full record

ArticleCase reports in hepatology2025

Primary Biliary Cholangitis With Incomplete Response to Conventional Therapies But Had Complete Response to Baricitinib: A Case Report.

Gi Eun Kim, Mariam Imran, Sherif Mostafa, Yasser Kamel

Abstract read
In one paragraph

Article in Case reports in hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gi Eun KimDepartment of Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar, hamad.qa.ORCID https://orcid.org/0000-0001-9713-4985
Mariam ImranDepartment of Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar, hamad.qa.ORCID https://orcid.org/0009-0002-1654-5219
Sherif MostafaDepartment of Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar, hamad.qa.ORCID https://orcid.org/0009-0007-9821-0119
Yasser KamelDepartment of Gastroenterology, Ambulatory Care Center, Hamad Medical Corporation, Doha, Qatar, hamad.qa.ORCID https://orcid.org/0000-0001-5037-2070

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary biliary cholangitis is a progressive disease with complications such as liver cirrhosis and hepatocellular carcinoma, and the treatment goal is to delay its progression. One of the markers for treatment response is alkaline phosphatase levels. Baricitinib has been used in one randomized controlled trial involving two patients to improve outcomes in unresponsive primary biliary cholangitis. We present a case of primary biliary cholangitis who had incomplete response to ursodeoxycholic acid, obeticholic acid, and fenofibrate but showed complete response to baricitinib in terms of sustained normalized alkaline phosphatase levels.

Indexed as

alkaline phosphatasebaricitinibcase reportprimary biliary cholangitis

Identifiers

PMID41473694
PMCPMC12747069

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.