Evidence map›Paper›PMID 41473681›Full record

ReviewMedicine international

Blood gas analysis: Clinical applications, interpretation and future directions (Review).

Mercedes Núñez Sanagustín, Joško Osredkar

Abstract readReview
In one paragraph

Review in Medicine international. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mercedes Núñez SanagustínInstitute of Clinical Chemistry and Biochemistry, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Joško OsredkarInstitute of Clinical Chemistry and Biochemistry, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood gas analysis represents a cornerstone diagnostic method in clinical practice, providing rapid assessment of respiratory and metabolic status through evaluation of pH, partial pressure of oxygen, partial pressure of carbon dioxide and bicarbonate. The present comprehensive review discusses recent advances in blood gas analysis, including emerging artificial intelligence (AI) applications, controversial practices in venous vs. arterial sampling and closed-loop management systems in critical care. The present review critically synthesizes evidence from recent systematic reviews and meta-analyses, addressing key controversies, such as the clinical utility of venous blood gas analysis with venous-to-arterial conversion technology (sensitivity, 97.6%; specificity, 36.9% for respiratory failure diagnosis) and automated interpretation systems. The present review encompasses physiological foundations, evidence-based clinical applications, structured interpretation methodologies and quality improvement strategies. Emphasis is placed on technological innovations including AI-assisted interpretation, non-invasive monitoring technologies and integration with closed-loop therapeutic systems. Through the analysis of >50 recent publications and current guidelines, the present review aimed to provide evidence-based recommendations for modern clinical practice, highlighting when venous sampling provides adequate diagnostic information, while reducing patient discomfort. Future perspectives include predictive algorithms for early clinical deterioration recognition and personalized diagnostic approaches. The present review aimed to provide unique clinical value by bridging traditional blood gas analysis with cutting-edge technological applications, providing practitioners with contemporary, evidence-based guidance for optimal patient care.

Indexed as

acid-base disordersarterial blood gas (ABG)artificial intelligence in medicineclinical diagnosticsrespiratory failure

Identifiers

PMID41473681
PMCPMC12746054

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.