Evidence map›Paper›PMID 41473645›Full record

ArticleCureus2025

Successful Spinal Anesthesia in a Patient With Severe Coagulopathy From Acute Liver Disease of Pregnancy Undergoing Cesarean Section: A Case Report.

Jingxia Meng, Shoaib Nawaz, Odai Khamash, Roni Mendonca, Ejaz Khan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jingxia MengAnesthesiology, New York Medical College, Metropolitan Hospital Center, New York, USA.
Shoaib NawazAnesthesiology, New York Medical College, Metropolitan Hospital Center, New York, USA.
Odai KhamashAnesthesiology, UPMC (University of Pittsburgh Medical Center) Harrisburg Hospital, Harrisburg, USA.
Roni MendoncaAnaesthesiology, Metropolitan Hospital Center, New York, USA.
Ejaz KhanAnesthesiology, New York Medical College, Metropolitan Hospital Center, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of acute fatty liver of pregnancy (AFLP) with significant coagulopathy despite no bleeding symptoms, which was managed with spinal anesthesia without adverse events. This phenomenon may not be attributable to coincidence alone. Upon reviewing the literature, standard coagulation tests fail to account for the simultaneous reduction in pro- and anticoagulant factors, leading to a misleading impression of coagulopathy and often overestimating the risk of bleeding. Thus, it is advised that coagulopathy tests associated with liver disease should not be used solely to dictate anesthesia decisions; a thorough history obtained from the patient, family, or medical records may be more informative than abnormal coagulation tests.

Indexed as

acute fatty liver of pregnancycesarean sectioncoagulopathyneuraxial anesthesiaspinal hematoma

Identifiers

PMID41473645
PMCPMC12747417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.