Evidence map›Paper›PMID 41473560›Full record

ArticleF&S reports2025

Serum human chorionic gonadotropin can predict live birth 7 days after frozen-thawed blastocyst transfer.

Nobuyuki Kidera, Tomonori Ishikawa, Toshihiro Kawamura, Naoyuki Miyasaka

Abstract read
In one paragraph

Article in F&S reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reading the hCG tea leaves.F&S reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nobuyuki KideraDenentoshi Ladies Clinic, Yokohama-shi, Kanagawa-ken, Japan.
Tomonori IshikawaDepartment of Perinatal and Maternal Medicine (Ibaraki), Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.
Toshihiro KawamuraDenentoshi Ladies Clinic, Yokohama-shi, Kanagawa-ken, Japan.
Naoyuki MiyasakaDepartment of Comprehensive Reproductive Medicine, Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the earliest timepoint at which serum human chorionic gonadotropin (hCG) can predict live birth after blastocyst frozen embryo transfer, and to determine the cutoff values for hCG levels on days 7-11 after frozen-thawed embryo transfer with blastocysts. Design: Single-center retrospective cohort study. Subjects: We investigated 18,491 cycles of frozen-thawed blastocyst transfers at our hospital between January 2016 and December 2022. Exposure: Not applicable. Main Outcome Measures: The hCG cutoff values for live birth on days 7-11 after frozen-thawed blastocyst transfer. Results: Receiver operating characteristic analysis between serum hCG levels and live birth after frozen-thawed blastocyst transfer showed area under the curve values of 0.962, 0.958, 0.954, 0.957, and 0.954, for days 7, 8, 9, 10, and 11, respectively. Serum hCG cutoff values from the 7th to 11th days after frozen-thawed blastocyst embryo transfer were 31.05 mIU/mL, 46.6 mIU/mL, 72.05 mIU/mL, 95.4 mIU/mL, and 159.9 mIU/mL, respectively. Conclusion: We determined the hCG cutoff values for live births after frozen-thawed blastocyst transfer. We suggest that it is possible to predict pregnancy outcomes as early as the 7th or 8th day after frozen-thawed blastocyst transfer.

Indexed as

area under curveblastocystembryo transferHuman chorionic gonadotropinlive birth

Identifiers

PMID41473560
PMCPMC12746892

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.