ArticleIJID regions2025
Viral hepatitis as a differential diagnosis of yellow fever suspected cases in Cameroon: Prevalence and molecular characterization.
Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Response to the Letter to the Editor regardingIJID regions · 2026Article
- Integrating viral hepatitis into yellow fever surveillance-reflections on Modiyinji et al.IJID regions · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The aim of this study was to determine the prevalence and genetic diversity of viral hepatitis among clinical cases of acute febrile jaundice initially suspected to be yellow fever (YF). Methods: We conducted a prospective cross-sectional study on YF-negative suspected samples collected between September 2024 and January 2025. The pentaplex polymerase chain reaction assay was used to detect five hepatotropic viruses. All detected viruses were genotyped, sequenced, and phylogenetically analyzed. Results: Among the 404 participants tested, viral hepatitis was diagnosed in 107 (26.5%; 95% confidence interval [CI]: 22.4-31.0%). The proportions were: hepatitis A virus (HAV) 70.1% (75/107), hepatitis B virus (HBV) 23.4% (25/107), hepatitis C virus (HCV) 3.7% (4/107), and hepatitis E virus (HEV) 2.8% (3/107). No sample was positive for hepatitis D virus, and no dual viral infections were detected. HAV was most common in patients under 15 years of age, while HBV was most common in patients aged over 15. The genotypes identified were HAV-IB and HAV-IIA, HBV-A and E, HCV-1 and HCV-4, and HEV-4. Conclusions: Our study shows that viral hepatitis plays a key role in acute febrile jaundice cases, which are often attributed to the YF virus in Cameroon.
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