Evidence map›Paper›PMID 41473459›Full record

ArticleCase reports in neurological medicine2025

Bilateral Cerebral Calcifications in Secondary Fahr's Syndrome.

Andreas Posa, Stefan Schob, Walter A Wohlgemuth, Malte E Kornhuber

Abstract read
In one paragraph

Article in Case reports in neurological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bilateral Cerebral Calcifications in Secondary Fahr's Syndrome.Case reports in neurological medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas PosaUniversity Clinic and Outpatient Clinic for Radiology, Martin Luther University Halle-Wittenberg, Halle, Germany, uni-halle.de.ORCID https://orcid.org/0000-0001-9807-6780
Stefan SchobUniversity Clinic and Outpatient Clinic for Radiology, Martin Luther University Halle-Wittenberg, Halle, Germany, uni-halle.de.ORCID https://orcid.org/0000-0003-2846-5443
Walter A WohlgemuthUniversity Clinic and Outpatient Clinic for Radiology, Martin Luther University Halle-Wittenberg, Halle, Germany, uni-halle.de.ORCID https://orcid.org/0000-0002-8076-6000
Malte E KornhuberUniversity Clinic and Outpatient Clinic for Neurology, Martin Luther University Halle-Wittenberg, Halle, Germany, uni-halle.de.ORCID https://orcid.org/0000-0003-3412-3263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fahr's syndrome is a rare, slowly progressive neurodegenerative disorder characterised by bilateral cerebral calcifications, mostly in the basal ganglia. These cerebral calcifications are composed of calcium and phosphate and are the result of disturbances in calcium-phosphate homeostasis. The clinical manifestations include neurological, neurocognitive and psychiatric symptoms. This article describes three rare cases of pronounced bilateral cerebral calcifications. All three patients were admitted to the hospital due to a first-time epileptic seizure. In all three cases, laboratory tests showed significant hypocalcaemia, and cerebral computed tomography showed pronounced bilateral cerebral calcifications in various brain areas. After calcium substitution and anticonvulsant treatment, the patients returned to their prehospital condition and were discharged home seizure free. The aim of this article is to highlight the clinical importance of long-term follow-up biochemical laboratory testing and neurocranial imaging in high-risk patients (e.g., after thyroidectomy) to prevent avoidable neurological and psychiatric complications through pharmaceutical and nutritional substitution therapy.

Indexed as

bilateral cerebral calcificationFahr’s diseasehypocalcaemiahypoparathyroidismsecondary Fahr’s syndrome

Identifiers

PMID41473459
PMCPMC12747057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.