Evidence map›Paper›PMID 41473444›Full record

ReviewFrontiers in oncology2025

Exploring the potential link between ADHD, anxiety, autism, and cancer risk.

Shreya Wajapeyee, Kristina Ford, Romi Gupta

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shreya WajapeyeeDepartment of Pediatrics Division of Developmental-Behavioral Pediatrics, University of Alabama at Birmingham (UAB), Birmingham, AL, United States.
Kristina FordDepartment of Pediatrics Division of Developmental-Behavioral Pediatrics, University of Alabama at Birmingham (UAB), Birmingham, AL, United States.
Romi GuptaDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodevelopmental and mental health disorders such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and anxiety disorders (AD) are increasingly being studied for their potential links to cancer risk. In this review, we present evidence indicating that ASD alone is not strongly associated with an increased risk of cancer. However, elevated risk is observed in subgroups with co-occurring intellectual disability or congenital anomalies. For ADHD, no direct biological link to cancer has been established, though behavioral factors and medication use remain areas of concern. Anxiety disorders may contribute indirectly to cancer risk through chronic stress and associated health behaviors, with some studies suggesting increased risk for specific cancers, such as prostate or urological cancers. Overall, this review highlights that increased cancer risk appears to be more closely related to co-occurring conditions and lifestyle factors than to the primary diagnoses themselves.

Indexed as

ADADHDanxietyASDautismcancer

Identifiers

PMID41473444
PMCPMC12745199

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.