Evidence map›Paper›PMID 41473295›Full record

ArticlebioRxiv : the preprint server for biology2025

Self-renewal of neuronal mitochondria through asymmetric division.

Tejashree Pradip Waingankar, Camryn Zurita, Angelica E Lang, Cliff Vuong, Ahmad Shami, Diana Bautista, Catherine Drerup, Samantha C Lewis

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tejashree Pradip WaingankarDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0001-8301-7315
Camryn ZuritaDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0001-8048-5690
Angelica E LangDepartment of Integrative Biology, University of Wisconsin-Madison, Madison, WI, USA.
Cliff VuongDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
Ahmad ShamiDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
Diana BautistaDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0002-6809-8951
Catherine DrerupDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0002-0219-3075
Samantha C LewisDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0001-6306-443X

Funding

Molecular Biology Across Scales Training ProgramT32GM148378 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI David Bilder, Elcin Unal · 2023 to 2026
$7.3M
Systems analysis of mitochondrial genome maintenance in physiological contextR35GM147218 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Samantha C Lewis · 2022 to 2026
$2.1M
Mechanism and function of retrograde mitochondrial transport in axonsR01NS124692 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Catherine M Drerup · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM147218NIGMS NIH HHS T32 GM148378NINDS NIH HHS R01 NS124692
6 · The paper itself

Abstract

Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs in highly polarized cells such as neurons remains poorly understood. Using high-resolution imaging in mouse peripheral sensory neurons and zebrafish larvae, we identified a sub-population of mitochondria enriched in mtDNA that are positioned at the collateral branch points of long sensory neurites, both

Identifiers

PMID41473295
PMCPMC12746139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.