Evidence map›Paper›PMID 41473171›Full record

ReviewFrontiers in medicine2025

Remimazolam in pediatric ambulatory anesthesia: a critical review and clinical perspective.

Yi Zhang, Hongchen Liu, Linyun Wang, Shuang Guo, Qingjun Zeng, Haishan Cui, Kaiyun Li

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi ZhangDepartment of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Hongchen LiuDepartment of Pediatrics, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Linyun WangNursing Department, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Shuang GuoDepartment of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Qingjun ZengDepartment of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Haishan CuiDepartment of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.
Kaiyun LiDepartment of Pediatrics, Maternal and Child Health Hospital of Wanzhou District, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of anesthesia for pediatric day surgery demands rapid onset, precise control, and predictable recovery. Remimazolam, an ultrashort-acting benzodiazepine with esterase-dependent metabolism, theoretically meets these needs. However, current pediatric evidence relies primarily on small observational studies with methodological limitations; data for infants under 2 years and long-term neurodevelopmental outcomes remain virtually absent. We conclude that while remimazolam holds promise, its use must be cautious and restricted to carefully selected scenarios until robust randomized controlled trials become available.

Indexed as

anesthesiacritical appraisalfuture perspectivespediatric day surgerypharmacodynamicspharmacokineticsremimazolamsafety

Identifiers

PMID41473171
PMCPMC12745394

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.