Evidence map›Paper›PMID 41473064›Full record

ArticleJTCVS open2025

Outcomes after cardiac surgery in patients with epilepsy: A nationwide analysis.

Alexander P Cabulong, Guangjin Zhou, Jean-Luc A Maigrot, Edward G Soltesz, Nicholas Schiltz, Siran M Koroukian

Abstract read
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Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Alexander P CabulongDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Guangjin ZhouDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Jean-Luc A MaigrotDepartment of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure Treatment and Recovery, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
Edward G SolteszDepartment of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure Treatment and Recovery, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
Nicholas SchiltzDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Siran M KoroukianDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess outcomes after cardiac surgery in patients with epilepsy. Methods: We queried the 2016-2019 Nationwide Readmissions Database for adult patients undergoing coronary artery bypass grafting, valve and aortic surgeries, or combination procedures. We compared mortality at index admission, complications, and 90-day readmissions between groups of patients with and without epilepsy before and after propensity-score matching. We used logistic regression analysis to evaluate the risk of adverse postoperative outcomes in the epilepsy group compared with their counterparts without epilepsy. Results: There were 1,104,303 patients identified who underwent cardiac surgery; of those, 15,492 (1.4%) had epilepsy. Patients with epilepsy more often had additional comorbidities, including congestive heart failure, chronic lung disease, and renal failure. Even after propensity-score matching, mortality at index admission (5.2% vs 3.6%), overall complications (44.2% vs 31.4%), and 90-day readmissions (27.3% vs 21.3%) were greater among patients with epilepsy than those without ( Conclusions: Further studies are necessary to identify strategies to improve outcomes after cardiac surgery in patients with epilepsy, as they have greater associated risks of postoperative mortality, complications, and readmission.

Indexed as

cardiac surgeryepilepsynational administrative databaseneurologic diseasereadmissionssurgical outcomes

Identifiers

PMID41473064
PMCPMC12745099

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.