Evidence map›Paper›PMID 41473049›Full record

ArticleJTCVS open2025

Flow benefits of pediatric arterial cannulae versus introducer sheaths as distal perfusion catheters in venoarterial extracorporeal membrane oxygenation.

Joshua G Crane, Mark S Slaughter, Steven C Koenig, Gretel Monreal

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua G CraneDepartment of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, Ky.
Mark S SlaughterDepartment of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, Ky.
Steven C KoenigDepartment of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, Ky.
Gretel MonrealDepartment of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, Ky.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We test the hypothesis that pediatric arterial ("peds art") cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer sheaths. Methods: Introducer sheaths (Teleflex 5, 6, 8 Fr) and peds art cannulae (Medtronic 6, 8, 10 Fr) were tested as DPCs in static and dynamic mock loops. Flow through each and flow loss caused by their intravascular obstructiveness was measured to calculate pressure gradient versus flow, intravascular obstruction flow, and resistances. Results: All 3 peds art cannulae tested delivered greater flows than the 3 introducer sheaths. The 10-Fr peds art cannula provided the most flow (0.97 L/min, 1500 rpm), whereas all 3 introducer sheaths provided much lower and nearly identical flows (only 0.18-0.20 L/min, 1500 rpm) despite their different diameters. The 10-Fr peds art cannula provided the most flow at equivalent head pressures despite being the most obstructive (least amount of flow around it, 2.0 L/min) relative to no DPC (2.5 L/min), resulting in the highest cumulative flow distally. Conclusions: The 10-Fr peds art cannula was the most beneficial DPC tested. All peds art cannulae tested possessed a better tradeoff of flow delivery versus intravascular obstructiveness compared to introducer sheaths, resulting in more favorable distal limb hemodynamics. The integrated stopcock with small holes (0.061'' = 4.65 Fr) on the introducer sheath's sidearm and at the 90° sidearm's attachment to the sheath's hub increase resistance. These chokepoints of introducer sheaths prevent sufficient flow to support distal limb perfusion as DPC.

Indexed as

arterial cannuladistal perfusion catheterDPCintroducer sheathlimb ischemiamock flow loopVA-ECMOvenoarterial extracorporeal membrane oxygenation

Identifiers

PMID41473049
PMCPMC12745103

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.