Evidence map›Paper›PMID 41473040›Full record

ArticleJTCVS open2025

Predictors of intraoperative donor heart turndown after initial acceptance for transplantation.

Armaan F Akbar, Alice L Zhou, Jessica M Ruck, Sorush Rokui, Dane Paneitz, Ahmet Kilic

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Armaan F AkbarDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.
Alice L ZhouDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.
Jessica M RuckDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.
Sorush RokuiDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.
Dane PaneitzDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.
Ahmet KilicDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Because of the low use of potential heart donors, it is important to maximize transplantation and minimize discard of accepted offers. We analyzed national registry data to investigate risk factors for intraoperative turndown of donor hearts that were initially accepted for transplantation. Methods: All adult deceased donors who donated ≥1 organs during the period from January 2005 to March 2023 in the United Network for Organ Sharing database and received an acceptance or provisional acceptance by a heart team were categorized by heart allograft use versus intraoperative turndown (ITD). We investigated risk factors for ITD using multivariable logistic regression adjusted for covariates with Results: Of 48,240 potential adult donors who received an acceptance from a heart transplant center, 43,401 (90.0%) of donors resulted in heart use, 1262 (2.6%) resulted in heart ITD, and 3577 (7.4%) resulted in heart nonuse for other reasons. ITD increased from 0.75% in 2005 to 2.2% in 2023 as a proportion of potential heart recoveries annually ( Conclusions: We identified several factors associated with intraoperative turndown that can inform anticipatory intraoperative evaluation and team coordination while preserving access to donor hearts.

Indexed as

donor managementdonor shortageheart transplantationorgan use

Identifiers

PMID41473040
PMCPMC12745084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.