Evidence map›Paper›PMID 41473004›Full record

ArticleHemaSphere2025

TLX1 translocation variants and enhancer hijacking influence clinical outcome in T-cell acute lymphoblastic leukemia.

Estelle Balducci, Thomas Steimlé, Agata Cieslak, Guillaume Charbonnier, Antoine Pinton, Mathieu Simonin, Charlotte Smith, Valentine Louis, Mélanie Féroul, Manon Delafoy and 10 more

Abstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Estelle BalducciLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.ORCID https://orcid.org/0000-0001-6792-1291
Thomas SteimléLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Agata CieslakLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Guillaume CharbonnierLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Antoine PintonLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Mathieu SimoninLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.ORCID https://orcid.org/0000-0002-0448-8811
Charlotte SmithLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Valentine LouisLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Mélanie FéroulLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Manon DelafoyLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Sophie KaltenbachLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Audrey BidetLaboratoire d'Hématologie Hôpital Haut-Lévêque Bordeaux France.
Béatrice GrangeLaboratoire d'Hématologie Centre Hospitalier Lyon Sud Pierre-Bénite France.
Lauren RigolletLaboratoire d'Hématologie CHU Saint-Etienne Saint-Etienne France.
Patrick VillareseLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Aurore TouzartLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.
Hervé DombretUniversité Paris Diderot, Institut Universitaire d'Hématologie, EA-3518 Hôpital Saint Louis Paris France.
André BaruchelHématologie et immunologie pédiatrique Hôpital Robert-Debré, AP-HP Paris France.
Nicolas BoisselUniversité Paris Diderot, Institut Universitaire d'Hématologie, EA-3518 Hôpital Saint Louis Paris France.
Vahid AsnafiLaboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris (AP-HP) Paris France.ORCID https://orcid.org/0000-0002-6255-5314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The T-cell Leukemia Homeobox 1 (

Identifiers

PMID41473004
PMCPMC12745038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.