Evidence map›Paper›PMID 41473003›Full record

ArticleHemaSphere2025

Health-related quality of life and symptom profile of patients with

Giovanni Caocci, Alessandro Costa, Francesca Palandri, Paola Guglielmelli, Andrea Patriarca, Alessandra Iurlo, Alessia Tieghi, Elisabetta Abruzzese, Thomas Baldi, Elena Rossi and 17 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Giovanni CaocciHematology Unit, Businco Hospital, ARNAS Brotzu, Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy.
Alessandro CostaHematology Unit, Businco Hospital, ARNAS Brotzu, Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy.ORCID https://orcid.org/0000-0002-7726-2936
Francesca PalandriIRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia "Seràgnoli" Bologna Italy.ORCID https://orcid.org/0000-0001-8367-5668
Paola GuglielmelliCRIMM, Center Research and Innovation of Myeloproliferative Neoplasms University of Florence, AOU Careggi Florence Italy.ORCID https://orcid.org/0000-0003-1809-284X
Andrea PatriarcaDivision of Hematology, Department of Translational Medicine University of Eastern Piedmont and Maggiore Charity Hospital Novara Italy.
Alessandra IurloHematology Division Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.ORCID https://orcid.org/0000-0002-4401-0812
Alessia TieghiDepartment of Hematology Azienda Unità Sanitaria Locale (AUSL)-IRCCS-Reggio Emilia Reggio Emilia Italy.
Elisabetta AbruzzeseHematology Unit S. Eugenio Hospital Rome Italy.
Thomas BaldiItalian Group for Adult Hematologic Diseases (GIMEMA) Data Center and Health Outcomes Research Unit Rome Italy.
Elena RossiInstitute of Haematology Catholic University, "A. Gemelli" Academic Hospital Rome Italy.
Eloise BeggiatoHematology AOU Città della Salute e della Scienza di Torino-Presidio Ospedaliero Molinette Turin Italy.
Monia MarchettiHematology and Transplant Unit University Hospital of Alessandria Alessandria Italy.
Carmen FavaDepartment of Clinical and Biological Sciences University of Turin Turin Italy.
Simona TomassettiHematology Unit, Department of Oncology and Hematology Infermi Hospital Rimini Rimini Italy.
Elisa RumiDepartment of Molecular Medicine University of Pavia Pavia Italy.
Claudio FozzaDepartment of Medicine, Surgery and Pharmacy University of Sassari Sassari Italy.
Mario LuppiSection of Hematology, Department of Medical and Surgical Sciences University of Modena and Reggio Emilia, AOU Modena Modena Italy.
Fabrizio PaneDepartment of Hematology and Bone Marrow Transplantation University Hospital Federico II Naples Italy.
Sara BigliardiOncology Unit Azienda Unità Sanitaria Locale Modena, Area Sud Sede di Sassuolo Sassuolo Italy.
Massimo BrecciaHematology, Department of Translational and Precision Medicine Sapienza University Rome Italy.
Elena Maria ElliHematology Division and Bone Marrow Transplant Unit San Gerardo Hospital, ASST Monza Monza Italy.
Francesca TartagliaItalian Group for Adult Hematologic Diseases (GIMEMA) Data Center and Health Outcomes Research Unit Rome Italy.
Olga MulasHematology Unit, Businco Hospital, ARNAS Brotzu, Department of Medical Sciences and Public Health University of Cagliari Cagliari Italy.
Paola FaziItalian Group for Adult Hematologic Diseases (GIMEMA) Data Center and Health Outcomes Research Unit Rome Italy.
Marco VignettiItalian Group for Adult Hematologic Diseases (GIMEMA) Data Center and Health Outcomes Research Unit Rome Italy.
Alessandro Maria VannucchiCRIMM, Center Research and Innovation of Myeloproliferative Neoplasms University of Florence, AOU Careggi Florence Italy.ORCID https://orcid.org/0000-0001-5755-0730
Fabio EfficaceItalian Group for Adult Hematologic Diseases (GIMEMA) Data Center and Health Outcomes Research Unit Rome Italy.ORCID https://orcid.org/0000-0002-5065-5166

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health-related quality of life (HRQoL) of patients with myeloproliferative neoplasms (MPNs) may be impaired across several domains. In this multicenter observational study, we evaluated HRQoL and symptoms in a cohort of MPN patients with validated measures, including the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30), the Myeloproliferative Neoplasm Symptom Assessment Form Total Symptom Score (MPN-SAF TSS), and the Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT-Fatigue) questionnaire. The primary objective was to compare the HRQoL profile of patients, by disease subtype, with that of the general population according to the EORTC QLQ-C30. A total of 572 patients with essential thrombocythemia (ET,

Identifiers

PMID41473003
PMCPMC12745044

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.