ArticleJCEM case reports2026
Clinical and Biochemical Progression in a Patient With Cortisol-Producing Adenoma.
Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The widespread use of imaging studies has led to an increased detection rate of adrenal incidentalomas. Among adrenal incidentalomas, mild autonomous cortisol secretion (MACS) is a common etiology. Development of overt Cushing syndrome (CS) from MACS is a rare event with an estimated prevalence of <1%. Herein, we report a case of cortisol-producing adenoma that demonstrated clinical and biochemical progression, resulting in the development of overt CS. A 50-year-old Japanese woman was referred for the evaluation of CS because of elevated blood pressure and peripheral edema. She had been followed for her left adrenal tumor and MACS before but was lost to follow-up for 2 years and 9 months. At presentation, she had cushingoid features. The 1-mg overnight dexamethasone suppression test indicated greater severity of autonomous cortisol secretion than that in the initial assessment. Imaging studies revealed that her left adrenal tumor increased in size. She underwent laparoscopic left adrenalectomy. Histologic and immunohistochemical examinations confirmed a cortisol-producing adenoma. Sequencing analysis identified a somatic
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.