Evidence map›Paper›PMID 41472922›Full record

ArticleProstate international2025

Transurethral water vapor therapy (Rezūm) for acute urinary retention with obstructive uropathy: a prospective cohort study with one-year follow-up.

Brian W H Siu, Jeremy M H Ho, Steffi K K Yuen, David K W Leung, Alex Q Liu, Chris H M Wong, Yvonne Y Y Chan, Ivan C H Ko, Chi Hang Yee, Jeremy Y C Teoh and 3 more

Abstract read
In one paragraph

Article in Prostate international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brian W H SiuSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Jeremy M H HoSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Steffi K K YuenSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
David K W LeungSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Alex Q LiuSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Chris H M WongSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Yvonne Y Y ChanSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Ivan C H KoSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Chi Hang YeeSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Jeremy Y C TeohSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Chi Fai NgSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Peter K F ChiuSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Ka Lun LoSH Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This prospective cohort study evaluates the safety and efficacy of transurethral water vapor therapy (Rezūm) in men with acute urinary retention (AUR) complicated by obstructive uropathy (acute renal impairment). Patients and methods: Obstructive uropathy was defined per 2012 Kidney Disease Improving Global Outcomes (KDIGO) Acute Kidney Injury (AKI) criteria. Rezūm was performed as an ambulatory procedure under local anesthesia. The primary outcome was the proportion of catheter-free patients at 3 and 12 months with stable renal function (i.e. serum creatinine not exceeding +0.3 mg/dL or 1.5 times baseline). Results: Twenty-three consecutive patients were recruited (August 2023-February 2024). Median age was 71 years (interquartile range [IQR]: 67-80) and mean ± standard deviation of prostate size was 57.9 ± 13.8 mL. At 3- and 12-month follow-up, 96% (22/23) were catheter-free with stable renal function. Median time to successful trial without catheter (TWOC) was 36.5 days (IQR: 27.5-42.8 days). Prostate size decreased by 36.8% (P < 0.001) at 3 months. Thirty-day readmissions occurred in 13% (3/23), all Clavien-Dindo grade 1-2. Conclusion: Rezūm shows promise as a safe and effective procedure in AUR with obstructive uropathy, providing durable catheter independence in high-risk patients. It expands minimally invasive surgical therapies (MISTs) indications, particularly as an ambulatory option under local anesthesia.

Indexed as

BPHObstructive nephropathyObstructive uropathyRezum

Identifiers

PMID41472922
PMCPMC12746255

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.