Evidence map›Paper›PMID 41472910›Full record

ArticleCase reports in nephrology2025

Adaptive Glomerular Hypertrophy in Kidney Transplants Associated With Focal Segmental Glomerulosclerosis: Report of Three Cases.

Autumn LaRocque, Ujwal Gautam, Nora Ewis, Richard Ugarte, Emily Daniel, John C Papadimitriou, Abdolreza Haririan, Cinthia B Drachenberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Autumn LaRocqueDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.ORCID https://orcid.org/0009-0008-0250-8904
Ujwal GautamDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.
Nora EwisDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.
Richard UgarteDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.
Emily DanielDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.
John C PapadimitriouDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.ORCID https://orcid.org/0000-0001-7963-5380
Abdolreza HaririanDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.
Cinthia B DrachenbergDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA, umaryland.edu.ORCID https://orcid.org/0000-0002-3104-5661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplant kidneys face increased functional demands in comparison to physiological conditions, and glomerular hypertrophy (GH) appears to be a common compensatory mechanism. Adaptive GH could contribute to improved graft function, but a so-called "maladaptive" response may lead to shortened graft survival. We assessed in three patients the mean glomerular diameter in donor preimplantation wedge biopsies and in subsequent posttransplant biopsies and correlated the glomerular size with Banff scores and clinical course. Mean glomerular size increased from 192.09 ± 28.65, 188.98 ± 19.86, and 168.96 ± 18.5 in preimplantation biopsies to 279.43 ± 50.6 (

Identifiers

PMID41472910
PMCPMC12747116

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.