Evidence map›Paper›PMID 41472854›Full record

ArticleiMeta2025

PhyloSuite v2: The development of an all-in-one, efficient and visualization-oriented suite for molecular dating analysis and other advanced features.

Dong Zhao, Tong Ye, Fangluan Gao, Ivan Jakovlić, Qiong La, Yindong Tong, Xiang Liu, Rui Song, Fei Liu, Zhong-Min Lian and 5 more

Abstract read
In one paragraph

Article in iMeta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
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  5. Reconstruction of an extinct soundscape reveals ultrasonic communication in the Jurassic.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  8. Natural Selection Drives Codon Usage Bias in the Mitochondrial Genome ofAnimals : an open access journal from MDPI · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A newInternational journal for parasitology. Parasites and wildlife · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dong ZhaoState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.ORCID https://orcid.org/0009-0008-9775-3784
Tong YeState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.
Fangluan GaoInstitute of Plant Virology Fujian Agriculture and Forestry University Fuzhou 350002 China.ORCID https://orcid.org/0000-0001-9031-9944
Ivan JakovlićState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.ORCID https://orcid.org/0000-0002-2461-3712
Qiong LaKey Laboratory of Biodiversity and Environment on the Qinghai-Tibetan Plateau, Ministry of Education, School of Ecology and Environment Xizang University Lhasa 850032 China.
Yindong TongSchool of Environmental Science and Engineering Tianjin University Tianjin 300072 China.
Xiang LiuState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.
Rui SongHunan Fisheries Research Institute and Aquatic Products Seed Stock Station Changsha 410153 China.
Fei LiuKey Laboratory of Biodiversity and Environment on the Qinghai-Tibetan Plateau, Ministry of Education, School of Ecology and Environment Xizang University Lhasa 850032 China.
Zhong-Min LianState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.
Hong ZouState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China.
Wen-Xiang LiState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China.
Gui-Tang WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China.
Benhe ZengInstitute of Fisheries Science Xizang Academy of Agriculture and Animal Husbandry Sciences Lhasa 850032 China.
Dong ZhangState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, and College of Ecology, Lanzhou University Lanzhou 730000 China.ORCID https://orcid.org/0000-0002-0902-6704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MCMCtree and r8s are among the most popular molecular dating tools in the current genomic era, but their utility is hampered by steep learning curves, particularly concerning input file formatting, the complexity of fossil calibration setup, tree visualization, and model selection. To enhance their usability and improve research efficiency, we developed three new tools: MDGUI (for molecular dating analysis), TimeTreeAnno (for timetree visualization), and MCMCTracer (for convergence assessment). We integrated these into the PhyloSuite v2 platform, along with MCMCtree and r8s plugins, to create a comprehensive molecular dating suite. Compared to existing solutions that we benchmarked, our toolkit offers a more intuitive interface and streamlined workflow, featuring visual calibration point configuration, support for multiple alignment formats, automated model selection and implementation for downstream analyses, one-click pause/resume functionality, multithreading acceleration, and on-demand MCMC convergence assessment and plotting. Furthermore, PhyloSuite v2 introduces other advanced features, including gene duplicate resolution during the extraction step, significantly accelerated data handling capabilities (specifically, format conversion and concatenation), deeper integration of the latest IQ-TREE models and functions, and further streamlining of the entire phylogenetic analysis workflow. The update also includes adaptation to high-resolution screens and numerous bug fixes. The source code for the new version of PhyloSuite is available at https://github.com/dongzhang0725/PhyloSuite.

Indexed as

annotationgraphical user interfaceMCMCtreemolecular datingphylogenetic analysisr8svisualization

Identifiers

PMID41472854
PMCPMC12747537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.