Evidence map›Paper›PMID 41472827›Full record

ArticlePatterns (New York, N.Y.)2025

AISleep: Automated and interpretable sleep staging from single-channel EEG data.

Xun Mai, Binghua Song, Manli Luo, Jun Zhu, Xu Jiang, Xiao Ma, Feng Lin, Xiaoqing Hu, Hanchuan Peng, Li Zhang and 1 more

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xun MaiResearch Center for Frontier Fundamental Studies, Zhejiang Lab, Hangzhou, China.
Binghua SongInstitute for Brain and Intelligence, Southeast University, Nanjing, China.
Manli LuoResearch Center for Frontier Fundamental Studies, Zhejiang Lab, Hangzhou, China.
Jun ZhuDepartment of Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Xu JiangDepartment of Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Xiao MaResearch Center for Frontier Fundamental Studies, Zhejiang Lab, Hangzhou, China.
Feng LinFuyao University of Science and Technology, Fujian, China.
Xiaoqing HuDepartment of Psychology, The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, China.
Hanchuan PengNew Cornerstone Science Laboratory, Institute for Brain and Intelligence, Fudan University, Shanghai, China.
Li ZhangDepartment of Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Yina WeiResearch Center for Frontier Fundamental Studies, Zhejiang Lab, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep staging is essential for understanding sleep physiology and diagnosing sleep-related disorders. However, traditional manual scoring is time-consuming and resource intensive, limiting its scalability for large-scale application. In this study, we introduce AISleep, an automated and interpretable unsupervised algorithm based on feature-weighted kernel density estimation (KDE), designed to stage sleep using only a single electroencephalogram (EEG) channel. AISleep was evaluated using both public benchmark datasets of healthy subjects and clinical datasets of patients with sleep disorders. It outperforms state-of-the-art (SOTA) unsupervised sleep staging algorithms in young, healthy subjects and demonstrates better generalizability compared to supervised models. Importantly, we observed that some key EEG features decline with age, which may contribute to reduced staging accuracy in older adults. This study presents a robust and interpretable unsupervised sleep staging algorithm with a lightweight design that makes it well suited to integration into portable devices, offering a practical and scalable solution for accurate, home-based sleep monitoring.

Indexed as

KDEkernel density estimationpower spectral densityPSDsingle-channel EEGsleepsleep stagingUMAPuniform manifold approximation and projectionunsupervised algorithm

Identifiers

PMID41472827
PMCPMC12745993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.