ReviewJournal of multidisciplinary healthcare2025
Best Evidence Summary for Preconception Management in Childbearing-Age Patients with Rheumatoid Arthritis.
Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pregnancy planning in women with rheumatic diseases: an integrated framework for risk stratification and multidisciplinary management.Rheumatology international · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The onset of rheumatoid arthritis (RA) most often occurs during the reproductive years. The chronic inflammatory state associated with the disease, along with the effects of therapeutic agents, contributes to a significantly higher incidence of adverse pregnancy outcomes compared to the general population. Standardized preconception management for childbearing-age patients with RA is an important prerequisite for achieving a safe pregnancy and promoting healthy offspring. However, existing evidence is scattered, and clinical practice lacks efficient evidence-based guidelines. Objective: To identify, evaluate, and summarize the best available evidence on preconception care for childbearing age with RA, and to provide evidence-based guidance for clinical nursing practice. Methods: A systematic search was conducted according to the "6S" pyramid model of evidence-based resources to identify evidence related to preconception management in childbearing-age patients with RA. Sources included clinical decision support systems, guidelines, databases, and professional association websites. The search covered all records from database inception until June 17, 2025. Results: A total of 11 publications were included, comprising 3 guidelines, 5 expert consensuses, 2 clinical decisions, and 1 systematic review. From these sources, a comprehensive set of 23 best evidence recommendations was formed across seven key aspects: general principles, fertility risk assessment, preconception screening, pre-pregnancy medication adjustment, fertility preservation, weight and nutrition management, and psychological support. Among the evidence gathered, a strong recommendation was made for 15 items, while the remaining 8 received a weak recommendation. Conclusion: This study provides a summary of best evidence for the preconception management of childbearing-age patients with RA, offering valuable guidance for clinical practice. To maximize patient benefits, healthcare providers should exercise careful clinical judgment when applying this evidence, taking into account the specific clinical context, individual patient circumstances, and preferences. Trial Registration: ES20258177.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.