Evidence map›Paper›PMID 41472671›Full record

ArticleCase reports in dermatological medicine2025

Eyelid Phenol Peeling as a Potential Alternative to Surgical Blepharoplasty: A Case Series.

Jana Dib El Jalbout, Caroline Silva Pereira, Maiara Onetta da Silva, Mariana Vilhena Ferreira, Nancy Emmanuel, Nelson Maurício Júnior, Roberto Tulli, Ivan Rollemberg

Abstract read
In one paragraph

Article in Case reports in dermatological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jana Dib El JalboutDepartment of Dermatology, Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon, lau.edu.lb.ORCID https://orcid.org/0000-0002-4911-3829
Caroline Silva PereiraDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.ORCID https://orcid.org/0009-0002-1560-589X
Maiara Onetta da SilvaDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.ORCID https://orcid.org/0009-0009-8153-5886
Mariana Vilhena FerreiraDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-2140-3760
Nancy EmmanuelDepartment of Dermatology, Faculty of Medicine of the University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-3963-0678
Nelson Maurício JúniorDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.
Roberto TulliDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.
Ivan RollembergDepartment of Clinical, Cosmetic and Surgical Dermatology, Human Clinic, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0003-4811-9484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenol peel is a deep peel used to treat conditions involving the reticular dermis such as scars, deep wrinkles, and lentigos and is an attractive alternative to surgical interventions for the rejuvenation of the eyelids and face. Patients who wish to undergo this procedure should be screened for the presence of any contraindications and should be counseled on the possible complications, which include arrhythmia, skin atrophy, scarring, acne eruption, and infection. We describe the cases of four women who underwent deep phenol peeling for the improvement of wrinkles and aging features around the eyelid area as a conservative alternative to surgical blepharoplasty. Patients were previously healthy with no absolute contraindication for the procedure. They were instructed to use the Kligman formula for 1 month prior to peeling. A nonsteroidal anti-inflammatory medication was given to the patient 30 mins before starting the procedure. The skin was cleansed with urea foam for 1 min, and excess product was removed with a dry and then a moistened gauze until the skin was clean. A 70% alcohol solution was then used to clean the skin area in which the peeling was desired. Phenol concentrated at 88% was applied using a damp cotton swab over multiple layers, until peeling was achieved. At the end of the procedure, a plastic occlusive mask was used to seal the area, and a postphenol occlusive ointment was applied over the periorbital region. Patients were instructed not to wash the area for 7-10 days and were prescribed Hyabak eye drops for dryness as well as oral analgesics as needed. No complications were reported in all cases. Phenol peeling is an easy, relatively safe and effective deep peeling technique that can be used to achieve the desired aesthetic outcomes in patients who wish to improve aging features and minimize the appearance of deep wrinkles without undergoing surgical intervention.

Indexed as

chemical peelingdeep peelingphenolskin rejuvenation

Identifiers

PMID41472671
PMCPMC12746350

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.