Evidence map›Paper›PMID 41472527›Full record

ArticleInternational journal of cancer2026

Race-specific temporal trends of HPV-related cancers in South Africa: An analysis of the South African National Cancer Registry, 2011-2022.

Adino T Tsegaye, Sizeka A Mashele, Jaimie Z Shing, Judith Mwansa-Kambafwile, Aimée R Kreimer, Carole Metekoua, Meredith S Shiels, Mazvita Muchengeti

Abstract read
In one paragraph

Article in International journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adino T TsegayeNational Cancer Institute, Rockville, Maryland, USA.ORCID https://orcid.org/0000-0001-9210-172X
Sizeka A MasheleNational Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa.
Jaimie Z ShingNational Cancer Institute, Rockville, Maryland, USA.
Judith Mwansa-KambafwileNational Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa.ORCID https://orcid.org/0000-0001-8552-2366
Aimée R KreimerNational Cancer Institute, Rockville, Maryland, USA.
Carole MetekouaNational Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-1331-8280
Meredith S ShielsNational Cancer Institute, Rockville, Maryland, USA.ORCID https://orcid.org/0000-0001-8390-6091
Mazvita MuchengetiNational Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-1955-923X

Funding

Intramural research program of the National Cancer Institute at the National Institutes of Health
6 · The paper itself

Abstract

Evaluating trends in HPV-related cancer rates by race is essential for identifying high-risk populations and improving prevention efforts. Using 2011-2022 South African National Cancer Registry data, we analyzed age-standardized incidence rates by race and sex across three periods (2011-2014, 2015-2018, 2019-2022) using linear regression. Significant increases were observed for oropharyngeal squamous cell carcinoma (SCC) among White females (p < .01), vulvar SCC among Asian (p < .01) and Black (p = .02) females, and anal SCC among Colored females and Black males (p < .01). Cervical carcinoma rates remained stable for most racial groups, except for the annual trends showing a 1.9% increase per year (95% CI = 1.0, 2.7) among White females. These findings suggest rising incidence rates for some HPV-related cancers across racial groups in South Africa. Further research is needed to explore the constellation of risk factors contributing to these trends and to guide targeted interventions.

Indexed as

Oropharyngeal NeoplasmsPapillomavirus InfectionsUterine Cervical NeoplasmsVulvar NeoplasmsAdultAgedFemaleHumansIncidenceMaleMiddle AgedRegistriesRisk FactorsSouth AfricaHPV‐related cancersincidence rateracial differencesSouth Africatemporal trend

Identifiers

PMID41472527
PMCPMC12963690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.