ArticleEuropean journal of oral sciences2026
Biomodification of dentin collagen with hydroalcoholic propolis extract: Impact on resin-dentin adhesion.
Article in European journal of oral sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
This in vitro study evaluated the effect of hydroalcoholic propolis extract (HPE) as a collagen cross-linking agent for preserving the dentin-adhesive interface. Dentin beams from human third molars were demineralized with 10% phosphoric acid and assigned to five treatments: distilled water (control), 6.5% grape seed extract (GSE), and HPE at 0.1%, 1%, or 10%. Elastic modulus (n = 10), dry mass variation (n = 10), and microtensile bond strength (µTBS, n = 8) were assessed after 24 h and after 6 months of storage. Collagen stability was analyzed using Fourier-transform infrared spectroscopy (n = 10). Elastic modulus was evaluated using Kruskal-Wallis and Friedman tests, dry mass variation, and µTBS with linear mixed-effects models. GSE produced the greatest increase in elastic modulus, followed by 1% and 0.1% HPE. After 6 months, all experimental groups maintained µTBS, except 0.1% HPE and the control, which showed reductions of approximately 30%. Spectroscopic analysis revealed increased Amide I and decreased Amide II bands in all treated groups, indicating enhanced collagen cross-linking. Overall, HPE-particularly at 1%-improved dentin collagen stability and contributed to the preservation of the adhesive interface over time.
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