Evidence map›Paper›PMID 41472327›Full record

ArticleSubstance use & misuse2026

Operationalizing Contingency Management to Improve Adherence and Retention in Methadone Treatment: A Scoping Review.

Thi Hue Nguyen, Thu Trang Nguyen, Thi Dieu Thuy Dao, Thi Thuyet Phung, Minh Giang Le, Thi Hai Van Hoang, Thi Huong Le, Vivian F Go, William C Miller

Abstract readScoping Review
In one paragraph

Article in Substance use & misuse, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thi Hue NguyenCenter for Training and Research on Substance Abuse and HIV, Hanoi Medical University, Hanoi, Vietnam.
Thu Trang NguyenCenter for Training and Research on Substance Abuse and HIV, Hanoi Medical University, Hanoi, Vietnam.
Thi Dieu Thuy DaoCenter for Training and Research on Substance Abuse and HIV, Hanoi Medical University, Hanoi, Vietnam.
Thi Thuyet PhungHanoi Center for Disease Control, Hanoi, Vietnam.
Minh Giang LeCenter for Training and Research on Substance Abuse and HIV, Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Thi Hai Van HoangInstitute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Thi Huong LeInstitute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Vivian F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
William C MillerDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA.

Funding

Vietnam Implementation Science Advancement: A Training Program to Improve HIV Prevention and CareD43TW011548 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VIVIAN F. GO, Huong Thi Le · 2021 to 2026
$1.7M
FIC NIH HHS D43 TW011548
6 · The paper itself

Abstract

backgroundContingency management, an evidence-based intervention, can be used to reinforce adherence and retention in methadone treatment. A literature synthesis on the delivery of contingency management for this purpose will facilitate the adoption of this intervention. Our scoping review addressed three questions: (1) What behaviors does contingency management target to promote adherence and retention in methadone treatment? (2) What incentives are used to reinforce these behaviors? and (3) What are the operational aspects of contingency management implementation in methadone treatment?

methodsWe searched original research articles in English in MEDLINE/PubMed and Embase. We summarized findings and identified research gaps through narrative analysis of the selected studies.

resultsWe identified 14 articles reporting 16 studies. Most studies were conducted in the United States and in large cities. Daily methadone consumption, attendance to scheduled appointments, and completion of individually tailored tasks were the target behaviors to promote adherence and retention. Contingency management was implemented in voucher-based and prize-based formats with high flexibility in adjusting the definition of a behavior achievement, value, and types of incentives to fit within clinical and budget constraints. Two highlighted aspects of contingency management delivery were how to identify the most appropriate and motivational incentives to a particular population and how to communicate with participants before and during the intervention.

conclusionContingency management is highly adaptable to different settings to improve treatment adherence and retention in methadone programs.

Indexed as

Medication AdherenceMethadoneOpiate Substitution TreatmentOpioid-Related DisordersAdherence InterventionsHumansMotivationMethadoneadherenceContingency managementmedications for opioid use disorderretentionsubstance abuse

Identifiers

PMID41472327
PMCPMC13538976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.