Evidence map›Paper›PMID 41472255›Full record

ArticleViruses2025

Timely Association of RSV Hospitalisation Waves in Children with the Detection of SARS-CoV-2 in the General Population in Eastern Bavaria.

Alexander Kiefer, Andreas Ambrosch, Benedikt M J Lampl, Fritz Schneble, Kai Rubarth, Stefan Vlaho, Matthias Keller, Michael Kabesch

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander KieferDepartment of Paediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.ORCID 0000-0003-2492-8850
Andreas AmbroschInstitute of Laboratory Medicine, Microbiology and Infection Prevention, Hospital of the Order of St. John, 93049 Regensburg, Germany.ORCID 0009-0006-4375-1949
Benedikt M J LamplDivision of Infection Control and Prevention, Regensburg Department of Public Health, 93059 Regensburg, Germany.ORCID 0000-0002-1008-7934
Fritz SchnebleDepartment of Paediatrics, 92637 Weiden, Germany.
Kai RubarthDepartment of Paediatrics, Sana Klinikum Hof, 95032 Hof, Germany.
Stefan VlahoDepartment of Paediatrics, Innklinikum Altötting, 84503 Altöttiing, Germany.
Matthias KellerKinderklinik Dritter Orden Passau, 94032 Passau, Germany.
Michael KabeschDepartment of Paediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Respiratory Syncytial Virus (RSV) season of 2023/2024 was conspicuously different from previous seasons, with an abrupt decrease in hospitalisation rates at the peak of the season, leading to two lower peaks instead of the expected one high peak of hospitalisations. Thus, we investigated whether there was an interference with other virus infection waves in the course of that RSV season.

methodsWe analysed RSV seasons since 2016 in children who were hospitalised due to an RSV infection in Eastern Bavaria and investigated epidemiological features of RSV seasons after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic at local, regional, and national levels.

resultsAnalysing patterns of four RSV seasons prior to and three seasons after the SARS-CoV-2 pandemic, we found that the paediatric RSV hospitalisation wave of the 2023/2024 season was weaker and less pronounced than expected. When we compared detailed local, regional, and national surveillance data of other viral infections, we found that paediatric RSV hospitalisation waves were anticyclical to SARS-CoV-2 infection waves, but not to rhinovirus or influenza waves in the general population. DISCUSSION: Our data suggests that concomitant SARS-CoV-2 infection waves in the general population may disrupt infection chains of RSV in children and, thus, decrease RSV-associated hospitalisation. This factor should be taken into account when assessing the effects of the upcoming RSV prophylaxis in the future.

Indexed as

COVID-19HospitalizationRespiratory Syncytial Virus InfectionsSARS-CoV-2ChildChild, PreschoolFemaleGermanyHumansInfantInfant, NewbornMaleRespiratory Syncytial Virus, HumanSeasonsepidemiologyhospitalisationRSVSARS-CoV-2

Identifiers

PMID41472255
PMCPMC12737403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.