Evidence map›Paper›PMID 41472214›Full record

ArticleViruses2025

Chronic Chikungunya Arthritis in Northeastern Brazil: An Association with Very Severe Joint Pain and Lack of Correlation with

Mariella Sousa Coêlho Maciel, Catharina Diniz de Brito Martins, Alan Gleison Moreira Dos Santos, Caroline Nobre Oliveira, Hygor Ferreira Fernandes, Raphael de Oliveira Rodrigues, Juliana Navarro Ueda Yaochite

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Characterization of the clinical forms of chronic chikungunya: an observational cohort study in Rio de Janeiro.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariella Sousa Coêlho MacielLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.ORCID 0000-0003-0509-5339
Catharina Diniz de Brito MartinsLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.
Alan Gleison Moreira Dos SantosLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.
Caroline Nobre OliveiraLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.
Hygor Ferreira FernandesInstituto Federal de Educação, Ciência e Tecnologia do Piauí, Parnaíba 64202-020, PI, Brazil.
Raphael de Oliveira RodriguesLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.
Juliana Navarro Ueda YaochiteLaboratório de Imunologia Celular e Molecular (LIMCEMO), Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Fortaleza 60430-370, CE, Brazil.ORCID 0000-0002-9666-5992

Funding

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico SUS/PPSUS-CE FUNCAP- PP3-0118- 00049.01.00/17
6 · The paper itself

Abstract

Chikungunya fever (CHIKF) affects thousands of people annually. Therefore, aspects involved in the pathogenesis of the disease must be further explored. In this study, we assessed the development of chronic chikungunya arthritis (CCA) and the single-nucleotide polymorphisms (SNPs) -174 G/C in the interleukin-6 (

Indexed as

ArthralgiaArthritisChikungunya FeverInterleukin-6Polymorphism, Single NucleotideTumor Necrosis Factor-alphaAdultAgedBrazilChikungunya virusChronic DiseaseFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleIL6 protein, humanInterleukin-6TNF protein, humanTumor Necrosis Factor-alphaarthritis chronic chikungunyainterleukin-6polymorphismstumor necrosis factor alpha

Identifiers

PMID41472214
PMCPMC12737619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.