Evidence map›Paper›PMID 41472211›Full record

ReviewViruses2025

The Host Immune Response to Enterovirus A71 (EV-A71): From Viral Immune Evasion to Immunopathology and Prognostic Biomarkers of Severe Disease-A Narrative Review.

Anna Andronik, Dawid Lewandowski, Artur Sulik, Kacper Toczylowski

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna AndronikDepartment of Pediatric Infectious Diseases, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0009-0001-9655-3595
Dawid LewandowskiDepartment of Pediatric Infectious Diseases, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0009-0006-9004-8623
Artur SulikDepartment of Pediatric Infectious Diseases, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0000-0002-8391-4793
Kacper ToczylowskiDepartment of Pediatric Infectious Diseases, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0000-0003-0309-6987

Funding

Medical University of Białystok B.SUB.25.106
6 · The paper itself

Abstract

Enterovirus A71 (EV-A71) is a critical global pathogen, primarily causing Hand-Foot-and-Mouth Disease (HFMD) but frequently leading to severe neurological complications, including fatal neurogenic pulmonary edema (PE). This review elucidates the complex interplay between viral pathogenesis and the host immune response. EV-A71 utilizes receptors like SCARB2 and PSGL-1 for entry, while its proteases (2A

Indexed as

Enterovirus A, HumanEnterovirus InfectionsHand, Foot and Mouth DiseaseHost-Pathogen InteractionsImmune EvasionAnimalsBiomarkersCytokinesHumansImmunity, InnatePrognosisT-Lymphocytes, RegulatoryBiomarkersCytokinesadaptive immunitybiomarkerscytokine stormenterovirus A71 (EV-A71)hand-foot-and-mouth disease (HFMD)immune evasionimmunopathologyneurotropism

Identifiers

PMID41472211
PMCPMC12737536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.